Valve prosthesis with movably attached claspers with apex
A valve prosthesis, implantation device, and methods for use are provided. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis. Alternative designs of the devices allow different methods for minimally invasive implantation of a sutureless valve prosthesis, including transapical and transcatheter approaches. Also provided is a delivery device for delivery of a medical prosthesis though minimally invasive means.
1. A valve prosthesis, comprising:
a support frame radially expandable between a compact condition and an expanded condition, said support frame having an outer surface and defining a central orifice about an axis along an inflow-outflow direction;
a plurality of flexible leaflets attached to the support frame to provide a one-way valve in the orifice when the support frame is in its expanded condition; and
at least one valve clasper movably attached to said support frame such that said at least one valve clasper is movable relative to said support frame along said, axis between a nesting position with the outer surface of the support frame and an engagement position with the valve annulus wherein said at least one valve clasper is physically separated from said support frame.
2. The valve prosthesis of claim 1 , wherein said support frame is comprised of a shape-memory material.
3. The valve prosthesis of claim 1 , wherein said support frame in its expanded condition has a radius r, and said at least one valve clasper is dimensioned to concentrically nest with the support frame when the support frame is in its expanded condition.
4. The valve prosthesis of claim 1 , wherein said at least one valve clasper is comprised of a first leg member, a second leg member and a u-shaped member, wherein each of said first leg member and said second leg member has a first end and a second end, and said first leg member and said second leg member are joined to the u-shaped member.
5. The valve prosthesis of claim 4 , wherein said second ends of the first and second leg members terminate in a detent.
6. The valve prosthesis of claim 4 , wherein said support frame is at least partially covered by a covering.
7. The valve prosthesis of claim 6 , wherein at least a portion of the first and second legs are disposed between the support frame and the covering.
8. The valve prosthesis of claim 4 , wherein each of the second ends of the first and second leg members terminates in a detent.
9. The valve prosthesis of claim 1 , wherein said at least one valve clasper is comprised of a u-shaped member.
10. The valve prosthesis of claim 9 , wherein said support frame is at least partially covered by a covering.
11. The valve prosthesis of claim 10 , wherein at least a portion of the u-shaped member is disposed between the support frame and the covering.
12. The valve prosthesis of claim 1 , wherein said at least one valve clasper is a multiplex unit comprising two or more u-shaped members and two or more apex members, wherein a first u-shaped member is permanently attached to a second u-shaped member via a first and second apex member and one clasper multiplex leg member.
13. The valve prosthesis of claim 12 , wherein said multiplex leg member terminates in a detent.
14. The valve prosthesis of claim 12 , wherein said support frame is at least partially covered by a covering.
15. The valve prosthesis of claim 14 , wherein at least a portion of the multiplex leg member is disposed between the support frame and the covering.
16. The valve prosthesis of claim 12 , wherein said multiplex leg member comprises one or more barbs.