IP Library Granted Patent US 8,853,247
Granted Patent B2
US 8,853,247 · App. 12/739,605 · Granted Oct 7, 2014

Oligomer-nitroimidazole anti-infective conjugates

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,853,247
App. No.
12/739,605
Granted
Oct 7, 2014
Kind
B2
Abstract

The invention provides (among other things) small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer.

Claims (11)

1. A compound of the structure:

wherein:

(a) is 2 or 3;

each instance of R 1 is hydrogen;

each instance of R 2 is hydrogen;

R 3 is selected from the group consisting of hydrogen, methyl and ethyl; and

(n) is an integer of from 3 to 7 inclusive.

2. The compound of claim 1 , wherein (a) is 2 and R 3 is selected from the group consisting of methyl and ethyl.

3. The compound of claim 1 , wherein (a) is 2 and R 3 methyl.

4. A composition comprising a compound of claim 1 and a pharmaceutically acceptable excipient.

5. A composition of matter comprising a compound of claim 1 , wherein the compound is present in a dosage form.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL 28571, FRAME 0141 Recorded Oct 14, 2015
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 036866/0700 →
GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Oct 6, 2015
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS COLLATERAL AGENT
Reel/Frame 036796/0562 →
GRANT OF SECURITY INTEREST Recorded Jul 17, 2012
From: NEKTAR THERAPEUTICS
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 028571/0141 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 25, 2010
From: REN, ZHONGXU; RIGGS-SAUTHIER, JENNIFER; BENTLEY, MICHAEL D.
To: NEKTAR THERAPEUTICS
Reel/Frame 024887/0970 →