IP Library › Granted Patent US 7,829,576
Granted Patent B2
US 7,829,576 · App. 12/750,558 · Granted Nov 9, 2010

Beloxepin and analogs for the treatment of pain

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Quick Facts
Patent No.
US 7,829,576
App. No.
12/750,558
Granted
Nov 9, 2010
Kind
B2
Abstract

This present disclosure provides methods of treating pain with beloxepin and/or beloxepin analogs.

Claims (18)

1. A method of treating pain in a mammal, comprising administering to a mammal suffering from pain an amount of beloxepin, or a salt thereof, effective to treat the pain.

2. The method of claim 1 in which the mammal is a human.

3. The method of claim 1 in which the beloxepin is administered parenterally.

4. The method of claim 1 in which the beloxepin is administered orally.

5. The method of claim 1 in which the pain is acute pain of nociceptive origin.

6. The method of claim 5 in which the pain is cancer pain.

7. The method of claim 5 in which the pain is surgical pain.

8. The method of claim 1 in which the pain is chronic pain of nociceptive origin.

9. The method of claim 8 in which the pain is inflammatory pain.

10. The method of claim 8 in which the pain is cancer pain.

11. The method of claim 1 in which the pain is chronic pain of non-nociceptive origin.

12. The method of claim 11 in which the pain is neuropathic pain.

13. The method of claim 1 in which the pain is inflammatory pain.

14. The method of claim 1 in which the pain is visceral pain.

15. The method of claim 1 in which the beloxepin, or a salt thereof, is administered to the mammal in the form of a composition.

16. The method of claim 15 in which the beloxepin is included in the composition as a salt.

17. The method of claim 15 in which the beloxepin is included in the composition as a free base.

18. The method of claim 15 in which the composition is formulated for oral administration.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Jul 24, 2015
From: ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT
To: CALIXA THERAPEUTICS, INC.; ADOLOR CORPORATION; CUBIST PHARMACEUTICALS, INC.
Reel/Frame 036180/0070 →
SECURITY AGREEMENT Recorded Nov 20, 2012
From: CUBIST PHARMACEUTICALS, INC.; ADOLOR CORPORATION; CALIXA THERAPEUTICS, INC.; CUBIST PHARMACEUTICALS HOLDINGS, INC.; CUBIST PHARMACEUTICALS U.S.
To: ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT
Reel/Frame 029339/0669 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 5, 2010
From: LE BOURDONNEC, BERTRAND; DOLLE, ROLAND E.
To: ADOLOR CORPORATION
Reel/Frame 024187/0367 →