Pesticidal formulations
View Patent ↗The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic combination of at least one A83543 compound and at least one macrocyclic lactone. The invention also relates to the use of the active composition in pesticidal formulations, the formulations themselves and to the various applications of those formulations as pesticides, specifically in controlling all species of Phthiraptera, Siphonaptera and Acarina pests, typically in domestic animals. Such applications include the control of such external Phthiraptera, Siphonaptera and Acarina pests in domestic animals including but not limited to sheep, cattle, poultry, pigs, goats, camelids, horses, dogs and cats.
1. A method of controlling a pest in a domestic animal comprising administering a systemically active oral composition comprising a combination of spinosad, or a salt thereof, and milbemycin oxime in a 10:1 to 100:1 weight/weight ratio, and at least one veterinarily acceptable carrier, diluent, or excipient, to said domestic animal, said domestic animal selected from sheep, cattle, poultry, pigs, goats, camellids, horses, and cats.
2. The method of claim 1 wherein said spinosad, or a salt thereof, and milbemycin oxime are from 0.1% -40% by weight of the composition.
3. The method of claim 2 wherein said at least one veterinarily acceptable carrier, diluent, or excipient is 60-99% by weight of the composition.
4. The method of claim 1 wherein said composition is in the form of a tablet, capsule, bolus, solution, suspension, or elixir.
5. The method of claim 1 wherein said composition comprises spinosad.
6. The method of claim 1 wherein said composition is in the form of a tablet, and said at least one veterinarily acceptable carrier, diluent, or excipient is a flavoring agent.
7. A method of controlling a pest in a domestic animal comprising administering a systemically active oral composition consisting essentially of a combination of spinosad, or a salt thereof, and milbemycin oxime in a 10:1 to 100:1 weight/weight ratio, and at least one veterinarily acceptable carrier, diluent, or excipient, to said domestic animal, said domestic animal selected from sheep, cattle, poultry, pigs, goats, camellids, horses, and cats.
8. The method of claim 7 wherein said spinosad, or a salt thereof, and milbemycin oxime are from 0.1% -40% by weight of the composition.
9. The method of claim 8 wherein said at least one veterinarily acceptable carrier, diluent, or excipient is 60-99% by weight of the composition.
10. The method of claim 7 wherein said composition is in the form of a tablet, capsule, bolus, solution, suspension, or elixir.
11. The method of claim 10 wherein said composition comprises spinosad.
12. The method of claim 11 wherein said composition is in the form of a tablet and said at least one veterinarily acceptable carrier, diluent, or excipient is a flavoring agent.
13. A systemically active oral composition comprising a combination of spinosad, or a salt thereof, and milbemycin oxime in a 10:1 to 100:1 weight/weight ratio, and at least one veterinarily acceptable carrier, diluent, or excipient.
14. The composition of claim 13 wherein said spinosad, or a salt thereof, and milbemycin oxime are from 0.1% -40% by weight of the composition.
15. The composition of claim 14 wherein said at least one veterinarily acceptable carrier, diluent, or excipient is 60-99% by weight of the composition.
16. The composition of claim 13 wherein said composition is in the form of a tablet, capsule, bolus, solution, suspension, or elixir.
17. The composition of claim 13 wherein said composition comprises spinosad.
18. The composition of claim 13 wherein said composition is in the form of a tablet, and said at least one veterinarily acceptable carrier, diluent, or excipient is a flavoring agent.
19. A method of controlling a pest in a domestic animal comprising administering the composition of claim 13 to said domestic animal.
20. The method of claim 19 where said domestic animal is a dog.
21. A systemically active oral composition consisting essentially of a combination of spinosad, or a salt thereof, and milbemycin oxime in a 10:1 to 100:1 weight/weight ratio, and at least one veterinarily acceptable carrier, diluent, or excipient.
22. The composition of claim 21 wherein said spinosad, or a salt thereof, and milbemycin oxime are from 0.1% -40% by weight of the composition.
23. The composition of claim 22 wherein said at least one veterinarily acceptable carrier, diluent, or excipient is 60-99% by weight of the composition.
24. The composition of claim 21 wherein said composition is in the form of a tablet, capsule, bolus, solution, suspension, or elixir.
25. The composition of claim 24 wherein said composition comprises spinosad.
26. The composition of claim 25 wherein said composition is in the form of a tablet and said at least one veterinarily acceptable carrier, diluent, or excipient is a flavoring agent.
27. A method of controlling a pest in a domestic animal comprising administering the composition of claim 26 to said domestic animal.
28. The method of claim 27 where said domestic animal is a dog.