Enhanced compositions containing cells and extracellular matrix materials
View Patent ↗Described are medical graft materials and devices having improved properties relating to their component profiles.
1. A composition comprising a decellularized extracellular matrix material exhibiting an angiogenic character and including native IgA at a level of no greater than 20 μg per gram, and added cells.
2. The composition of claim 1 , wherein the cells are eukaryotic cells.
3. The composition of claim 2 , wherein the cells are endothelial cells.
4. The composition of claim 2 , wherein the cells are fibroblastic cells.
5. The composition of claim 1 , wherein the cells are mammalian cells.
6. The composition of claim 1 , wherein the cells are human cells.
7. The composition of claim 6 , wherein the extracellular matrix material is in particulate form.
8. The composition of claim 6 , wherein the extracellular matrix material is in sheet form.
9. The composition of claim 6 , wherein the extracellular matrix material is in gel form.
10. The composition of claim 1 , wherein the extracellular matrix material retains native FGF-2.