IP Library Granted Patent US 9,125,983
Granted Patent B2
US 9,125,983 · App. 12/762,307 · Granted Sep 8, 2015

Hydraulically actuated pump for fluid administration

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Quick Facts
Patent No.
US 9,125,983
App. No.
12/762,307
Granted
Sep 8, 2015
Kind
B2
Abstract

A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.

Claims (29)

1. A fluid delivery device comprising:

a hydraulic housing having a piston configured to sealingly slide along an inner wall of the hydraulic housing and separate the hydraulic housing into a hydraulic pump chamber and a fluid reservoir, the hydraulic pump chamber having a hydraulic fluid and configured to urge the piston along the inner wall to deliver a fluid in the fluid reservoir to a patient;

a first actuator;

a first hydraulic reservoir chamber having the hydraulic fluid and coupled between the first actuator and the hydraulic pump chamber, the first actuator being configured to urge the hydraulic fluid in the first hydraulic reservoir chamber into the hydraulic pump chamber;

a flow restrictor fluidly coupling the first hydraulic reservoir chamber and the hydraulic pump chamber;

a second hydraulic reservoir chamber having the hydraulic fluid and fluidly coupled with the hydraulic pump chamber; and

a second actuator configured to urge the hydraulic fluid from the second hydraulic reservoir chamber into the hydraulic pump chamber, independent of the first actuator.

2. The fluid delivery device of claim 1 , wherein the flow restrictor and the first actuator are configured to transfer the hydraulic fluid from the first hydraulic reservoir chamber to the hydraulic pump chamber to deliver the fluid from the fluid reservoir at a sustained basal rate.

3. The fluid delivery device of claim 2 , wherein the sustained basal rate is constant.

4. The fluid delivery device of claim 2 , wherein the sustained basal rate is over a period of more than 5 hours.

5. The fluid delivery device of claim 2 , wherein the sustained basal rate is over a period of approximately 24 hours.

6. The fluid delivery device of claim 1 , wherein the first and second actuators are compression springs.

7. The fluid delivery device of claim 1 , wherein the first and second actuators are coupled to the hydraulic pump chamber in parallel.

8. The fluid delivery device of claim 2 , wherein the second actuator is configured to selectably transfer the hydraulic fluid from the second hydraulic reservoir chamber into the hydraulic pump chamber at discrete intervals to deliver a bolus dosage of the fluid in addition to the sustained basal rate.

9. The fluid delivery device of claim 1 , wherein the first actuator includes two or more springs.

10. The fluid delivery device of claim 1 further comprising the fluid in the fluid reservoir, wherein the fluid comprises insulin.

11. The fluid delivery device of claim 1 , wherein the hydraulic fluid has a viscosity of approximately ISO VG 1500 or more when in use.

12. The fluid delivery device of claim 1 , further comprising a moveable piston separating the hydraulic pump chamber and the second actuator.

13. The fluid delivery device of claim 1 , wherein the hydraulic pump chamber and the fluid reservoir are comprised of a polymer.

14. The fluid delivery device of claim 1 , wherein the second hydraulic reservoir is positioned between the second actuator and the hydraulic pump chamber.

15. The fluid delivery device of claim 1 , wherein the flow restrictor is a fixed aperture.

16. The fluid delivery device of claim 1 , wherein the piston is a single piston that contacts the fluid in the fluid reservoir on one side and the hydraulic fluid on another side.

17. A fluid delivery device comprising:

a hydraulic housing having a piston configured to sealingly slide along an inner wall of the hydraulic housing and separate the hydraulic housing into a hydraulic pump chamber and a fluid reservoir, the hydraulic pump chamber having a hydraulic fluid and configured to urge the piston along the inner wall to deliver a fluid in the fluid reservoir to a patient;

a first hydraulic reservoir chamber having the hydraulic fluid;

a fixed aperture flow restrictor fluidly coupling the first hydraulic reservoir chamber and the hydraulic pump chamber, the fixed aperture flow restrictor configured to control the rate the hydraulic fluid flows between the first hydraulic reservoir chamber and the hydraulic pump chamber;

a first actuator coupled to the first hydraulic reservoir chamber and configured to continuously deliver the hydraulic fluid from the first hydraulic reservoir chamber to the hydraulic pump chamber for a period of time;

a second hydraulic reservoir chamber fluidly coupled to the hydraulic pump chamber, independent of the first hydraulic reservoir chamber; and

a second actuator coupled to the second hydraulic reservoir chamber and operable independent of the first actuator and at discrete intervals during the period of time to periodically deliver the hydraulic fluid from the second hydraulic reservoir chamber to the hydraulic pump chamber independent of and in addition to the continuous delivery of the hydraulic fluid from the first hydraulic reservoir chamber.

Assignments (8)
SALE ORDER / RELEASE OF SECURITY INTEREST Recorded Aug 18, 2025
From: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: ZEALAND PHARMA A/S
Reel/Frame 072509/0386 →
PATENT SECURITY AGREEMENT Recorded Aug 12, 2025
From: MANNKIND CORPORATION
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 072444/0525 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 2, 2022
From: ZEALAND PHARMA A/S
To: MANNKIND CORPORATION
Reel/Frame 060984/0295 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 6, 2020
From: VALERITAS, INC.
To: ZEALAND PHARMA A/S
Reel/Frame 052859/0390 →
SHORT-FORM PATENT SECURITY AGREEMENT Recorded May 28, 2013
From: VALERITAS, INC.
To: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
Reel/Frame 030497/0800 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2010
From: GONNELLI, ROBERT R.; MCALLISTER, DEVIN V.; LEVESQUE, STEVEN F.
To: BIOVALVE TECHNOLOGIES, INC.
Reel/Frame 024249/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2010
From: BIOVALVE TECHNOLOGIES, INC.
To: VALERITAS, LLC
Reel/Frame 024249/0006 →
CHANGE OF NAME Recorded Apr 17, 2010
From: VALERITAS, LLC
To: VALERITAS, INC.
Reel/Frame 024249/0016 →