Apparatus, system and method for predictive modeling to design, evaluate and optimize ophthalmic lenses
An apparatus, system and method for predictive modeling to design, evaluate and optimize ophthalmic lenses is disclosed. Ophthalmic lenses may include, for example, contacts, glasses or intraocular lenses (IOLs). The apparatus, system and method may include a design tool for designing a lens for implantation in an eye having a plurality of characteristics, a simulator for simulating performance of the lens in at least one modeled eye having the plurality of characteristics, at least one input for receiving clinical performance of the lens in the eye having the plurality of characteristics, a comparator for comparing outcomes of the clinical performance and the simulated performance, and an optimizer for optimizing a subsequent one of the outcome of the clinical performance responsive to modification of the lens in accordance with modification to the simulated performance.
1. A system for optimizing a clinical implementation of an ophthalmic lens, wherein the ophthalmic lens is indicated for treating at least one condition of a set of eyes, comprising:
an eye model associated with at least one processor, wherein the eye model is indicative of residual accommodation, and wherein the at least one condition comprises off-axis vision, post-LASIK patients, and combinations thereof;
a simulator provided by the at least one processor that models the ophthalmic lens in the eye model having at least a first characteristic, wherein the simulator outputs a first outcome, the first outcome comprising simulated visual acuity at multiple levels of defocus of the ophthalmic lens in the eye model;
at least one clinical input to the at least one processor comprising at least a second characteristic of a clinical eye associated with the clinical implementation, wherein the second characteristic at least substantially overlaps the first characteristic, and a second outcome, the second outcome comprising clinical visual acuity at multiple levels of defocus indicative of the clinical implementation of the ophthalmic lens; and
a comparator instantiated by the at least one processor that compares the simulated visual acuity at multiple levels of defocus and the clinical visual acuity at multiple levels of defocus, and then compares differences between the simulated visual acuity at multiple levels of defocus and the clinical visual acuity at multiple levels of defocus to a predetermined tolerance threshold;
wherein the at least one processor modifies the eye model to optimize at least the simulated visual acuity at multiple levels of defocus to bring the differences within the predetermined tolerance threshold.
2. The system of claim 1 , wherein the first outcome additionally comprises a simulated contrast sensitivity and the second outcome additionally comprises a clinical contrast sensitivity for at least one predetermined viewing condition, and wherein the comparator additionally compares the simulated contrast sensitivity and the clinical contrast sensitivity, and additionally compares differences between the simulated contrast sensitivity and the clinical contrast sensitivity to a second predetermined tolerance threshold.
3. The system of claim 2 , wherein the second predetermined tolerance threshold comprises a comparative level of contrast sensitivity.
4. The system of claim 1 , wherein the second outcome additionally comprises a clinical outcome parameter.
5. The system of claim 1 , wherein at least one of the at least one clinical input comprises a remote input.
6. The system of claim 5 , wherein the remote input is provided over at least one network.
7. The system of claim 1 , wherein at least one of the at least one clinical input comprises a local input.
8. The system of claim 1 , wherein the predetermined tolerance threshold comprises a comparative level of visual acuity.
9. The system of claim 1 , further comprising at least one graphical user interface, wherein the at least one clinical input is provided from, and the optimization is provided to, the at least one graphical user interface.
10. The system of claim 1 , wherein the ophthalmic lens comprises an intraocular lens.
11. A method of optimizing a design of an ophthalmic lens, comprising:
receiving a first lens design-for the ophthalmic lens;
simulating, by using an eye model, a simulated visual acuity at multiple levels of defocus provided by the first lens design and residual accommodation; in at least one modeled eye having a plurality of first characteristics, wherein the plurality of first characteristics include at least one of off-axis vision, post-LASIK patients, and combinations thereof;
receiving a clinical visual acuity at multiple levels of defocus of the first lens design in a plurality of patient eyes having a plurality of second characteristics;
comparing the clinical visual acuity at multiple levels of defocus and the simulated visual acuity at multiple levels of defocus; and
optimizing, using at least one processor, the first lens design to a second lens design in accordance with the comparing;
wherein the comparing comprises comparing a difference between the clinical visual acuity at multiple levels of defocus and the simulated visual acuity at multiple levels of defocus to a predetermined tolerance threshold.
12. The method of claim 11 , wherein the optimizing is responsive to different weightings of one of the plurality of first characteristics.
13. The method of claim 12 , wherein the comparing is based on the different weightings.
14. The method of claim 11 , wherein the optimizing is responsive to different weightings of the simulated visual acuity at multiple levels of defocus and the clinical visual acuity at multiple levels of defocus.