IP Library Granted Patent US 8,455,015
Granted Patent B2
US 8,455,015 · App. 12/771,705 · Granted Jun 4, 2013

Compositions and methods for treating

Inventors: Ying-Ying Gao (Quanzhou, CN); Scheffer C. G. Tseng (Pinecrest, FL)
Assignee: Tissuetech, Inc.
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Quick Facts
Patent No.
US 8,455,015
App. No.
12/771,705
Granted
Jun 4, 2013
Kind
B2
Abstract

Compositions containing about 0.6% to about 20% of tea tree oil are described. Some compositions are in the form of solutions, suspensions, spray, lotions, gels, pastes, medicated sticks, balms, cleansers (including shampoos and soaps), creams, or ointments. Also described are compositions and methods for use in treating ocular Demodex infestations and related conditions using such compositions.

Claims (2)

1. A method of treating an ocular Demodex infestation or Demodex -induced blepharitis in an individual in need thereof, comprising administering to the individual a therapeutically-effective amount of a composition consisting essentially of:

about 1% up to, but not including, about 20% w/w of terpinen-4-ol as an active agent, provided that the composition does not include tea tree oil; and at least one ophthalmically acceptable excipient.

Assignments (9)
SUPPLEMENT TO PATENT SECURITY AGREEMENT Recorded Jun 23, 2023
From: PRN PHYSICIAN RECOMMENDED NUTRICEUTICALS, LLC
To: CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT
Reel/Frame 064074/0182 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 13, 2023
From: ACUMEN HEALTH HOLDINGS
To: PRN PHYSICIAN RECOMMENDED NUTRICEUTICALS, LLC
Reel/Frame 063937/0155 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 13, 2023
From: BIOTISSUE HOLDINGS INC.
To: ACUMEN HEALTH HOLDINGS, LLC
Reel/Frame 063937/0142 →
CHANGE OF NAME Recorded May 10, 2023
From: TISSUETECH, INC.
To: BIOTISSUE HOLDINGS INC.
Reel/Frame 063591/0802 →
RELEASE OF SECURITY INTEREST Recorded May 4, 2023
From: MIDCAP FUNDING IV TRUST
To: TISSUETECH, INC.
Reel/Frame 063540/0567 →
RELEASE OF SECURITY INTEREST Recorded May 4, 2023
From: MIDCAP FINANCIAL TRUST
To: TISSUETECH, INC.
Reel/Frame 063540/0575 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT - TERM LOAN Recorded May 18, 2022
From: TISSUETECH, INC.; BIO-TISSUE, INC.; AMNIOX MEDICAL, INC.
To: MIDCAP FINANCIAL TRUST
Reel/Frame 060116/0413 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT - REVOLVING LOAN Recorded May 18, 2022
From: TISSUETECH, INC.; BIO-TISSUE, INC.; AMNIOX MEDICAL, INC.
To: MIDCAP FUNDING IV TRUST
Reel/Frame 060116/0468 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 9, 2010
From: GAO, YING-YING; TSENG, SCHEFFER C.G.
To: TISSUETECH, INC.
Reel/Frame 024661/0825 →
Continuity (2)
Division 11846961 · Aug 29, 2007
Related Publication 20100273870A1 · Oct 28, 2010