Systems for monitoring a patient's neurological disease state
View Patent ↗The present invention provides methods and systems for modulating a patient's neurological disease state. In one embodiment, the system comprises one or more sensors that sense at least one signal that comprise a characteristic that is indicative of a neurological disease state. A signal processing assembly is in communication with the one or more sensors and processes the at least one signal to estimate the neurological disease state and to generate a therapy to the patient that is based at least in part on the estimated neurological disease state. A treatment assembly is in communication with the signal processing assembly and delivers the therapy to a nervous system component of the patient.
1. A system for modulating a patient's neurological disease state, the system comprising:
one or more sensors that sense at least one signal that comprise a characteristic that is indicative of a neurological disease state;
a signal processing assembly in communication with the one or more sensors that processes the at least one signal using a disease state processor to estimate the neurological disease state and to adjust a parameter of a therapy to the patient as a function of the estimated neurological disease state;
a treatment assembly in communication with the signal processing assembly, wherein said treatment assembly delivers the therapy to a nervous system component of the patient; and
a patient interface module that communicates with a patient the estimated disease state, said patient interface module being in communication with the signal processing assembly and external to the patient's body.
2. The system of claim 1 wherein the treatment assembly comprises an electrode array.
3. The system of claim 2 wherein the electrode array is coupled to a peripheral nerve.
4. The system of claim 2 wherein the electrode array comprises a vagus nerve electrode array.
5. The system of claim 1 wherein the electrode array is positionable intracranially.
6. The system of claim 1 wherein the patient interface module facilitates monitoring of a time history of at least one estimated disease state.
7. The system of claim 1 wherein the patient interface module facilitates monitoring of a future disease state.
8. The system of claim 1 wherein the signal processing assembly is implanted within the patient's body.
9. The system of claim 1 wherein the signal processing assembly implements a control law that determines the therapy to control the neurological disease state.
10. The system of claim 1 wherein said signal processing assembly calculates the output of a control law.
11. The system of claim 1 wherein said signal processing assembly calculates at least one parameter to specify the therapy to control the neurological disease state.
12. The system of claim 1 wherein the signal processing assembly comprises a memory for storing at least one of the estimated neurological disease state and parameters of the therapy.