Expandable devices and methods for treating a nasal or sinus condition
Described here are expandable devices and methods for using them. The devices generally comprise a hub and a plurality of legs extending therefrom. In some variations, the hub may comprise one or more domed portions, tapered portions, or the like. The legs may comprise one or more straight segments, one or more curved segments, or a combination thereof. The devices may comprise one or more polymers, and/or one or more portions of the device may be configured to biodegrade. In other variations, the device may be configured to release one or more drugs therefrom. Additionally, in some variations the devices may be configured to be self-expandable from a low-profile configuration to an expanded configuration.
1. A method for treating a sinus condition, comprising:
advancing a device, the device having a proximal end and a distal end, and a low-profile configuration and an expanded configuration, in the low-profile configuration to one or more nasal passageways or paranasal sinus cavities, wherein the device comprises a biodegradable domed hub at the proximal end of the device and a plurality of biodegradable legs attached to the biodegradable domed hub, wherein each of the legs comprises a first inwardly curved segment extending distally from the biodegradable domed hub, and a second straight segment extending outward from the distal end of the first inwardly curved segment,
wherein the device is advanced using a delivery device comprising a shaft and a sheath, the shaft having a distal portion disposed within the domed hub when the device is in the low profile configuration, and the sheath having a proximal portion and a distal portion, the distal portion of the sheath holding the distal ends of the straight segments of the legs in the low-profile configuration, and wherein the legs of the device are releasably mounted on the shaft when the device is in the low-profile configuration; and
deploying the device, wherein deploying the device comprises retracting the sheath, such that at least a portion of at least one of the plurality of lees contacts surrounding tissue, and the device expands into the expanded configuration.
2. The method of claim 1 , wherein the sinus condition is nasal polyposis, and wherein the surrounding tissue comprises one or more nasal polyps.
3. The method of claim 1 , wherein the domed hub comprises one or more slots, channels, or passageways passing at least partially therethrough.
4. The method of claim 1 , wherein the device is self-expandable between the low-profile configuration and the expanded configuration.
5. The method of claim 1 , wherein the device comprises one or more injection-molded polymers.
6. The method of claim 1 , wherein at least one of the plurality of biodegradable legs has a rectangular cross-sectional shape.
7. The method of claim 6 , wherein the at least one rectangular leg comprises a first longitudinal channel.
8. The method of claim 7 , wherein the at least one rectangular leg comprises a second longitudinal channel, wherein the first and second longitudinal channels extend along opposite sides of the rectangular leg.
9. The method of claim 1 , wherein the device further comprises a hub extension.
10. The method of claim 1 , wherein the device further comprising one or more meshes, membranes or films connecting at least two legs.
11. The method of claim 1 , wherein at least one of the plurality of biodegradable legs of the device comprises one or more anchoring components.
12. The method of claim 1 , wherein the device comprises one or more drug-reservoirs.
13. The method of claim 1 , wherein the device comprises one or more drug-releasing coating layers.
14. The method of claim 1 , wherein the device comprises one or more extruded polymers.
15. The method of claim 1 . wherein at least one of the plurality of biodegradable legs has an oval cross-sectional shape.
16. The method of claim 1 , wherein at least one of the plurality of biodegradable legs has a circular cross-sectional shape.