HPTS-mono and bis Cys-MA polymerizable fluorescent dyes for use in analyte sensors
View Patent ↗Novel fluorescent dyes are disclosed for use in analyte detection. In particular, mono- and bis-substituted HPTS dyes and methods of making them are provided.
1. The compound:
2. A method of making the compound of claim 1 comprising the steps of:
3. A hydrogel comprising a compound of claim 1 .
4. A glucose sensor comprising a compound of claim 1 .
5. The glucose sensor of claim 4 , further comprising a quencher moiety comprising boronic acid.
6. The glucose sensor of claim 5 , wherein said quencher moiety comprising boronic acid is 3,3′-oBBV:
7. A glucose sensor comprising a hydrogel of claim 3 .
8. A glucose sensor of claim 7 wherein the hydrogel further comprises a quencher moiety comprising boronic acid.
9. A glucose sensor of claim 8 , wherein said quencher moiety comprising boronic acid is 3,3′-oBBV.