Self-sealing compositions
View Patent ↗Medical devices having a wound closure device and a reinforcing material are reacted in situ to create a self-sealing implant.
1. A self-sealing implant comprising: at least one staple and a polymeric buttress, wherein upon interaction of the at least one staple and the buttress, a hydrogel is formed.
2. The self-sealing implant according to claim 1 , wherein at least one of the staple and the buttress further comprises a material selected from the group consisting of succinimidyl containing polymers and multifunctional primary amines.
3. The self-sealing implant according to claim 1 , wherein the self-sealing implant further comprises at least one reactive component selected from the group consisting of electrophilic functional groups and nucleophilic functional groups.
4. A method comprising the steps of:
positioning a polymeric buttress comprising a first reactive component on a tissue;
firing at least one staple comprising a second, complementary reactive component from a stapler, the at least one staple contacting the buttress; and,
initiating a chemical reaction.
5. The method according to claim 4 , wherein either the first or second complementary reactive components comprise a polymer drug.
6. The method according to claim 4 , wherein either the first or second complementary reactive components comprise a medicinal agent.
7. A method comprising the steps of:
positioning a polymeric buttress comprising a first reactive component on a tissue;
firing at least one staple comprising a second, complementary reactive component from a stapler, the at least one staple contacting the buttress; and,
forming a hydrogel.