Physiological coolants based on lactoyl esters of menthyl lactate
View Patent ↗A method of imparting a physiological cooling effect to a consumer product is disclosed. The method comprises formulating into the consumer product a composition comprising at least one lactoyl ester of menthyl lactate. Also disclosed is a method of providing physiological cooling by contacting skin or mucous membranes with the lactoyl ester compositions. Coolants comprising the lactoyl esters and additional coolants are also disclosed. The lactoyl esters are conveniently prepared from menthol and lactic acid.
1. A consumer product selected from the group consisting of foods, beverages, toiletries, lotions, medications, and pharmaceuticals, said consumer product comprising from 0.1 ppm to 5 wt. % of at least one lactoyl ester of menthyl lactate, wherein the liquid mixture further comprises a coolant selected from the group consisting of substituted cyclohexanols and their esters, carboxamides, menthone ketals, and mixtures thereof.
2. The consumer product of claim 1 wherein the food is a confection or chewing gum.
3. The consumer product of claim 1 wherein the toiletry is a cosmetic, toothpaste, mouthwash, shampoo, or lotion.
4. The consumer product of claim 1 wherein the lactoyl ester is menthyl lactoyl lactate (MLL).
5. The consumer product of claim 4 wherein the MLL is prepared by reacting l-menthol and an excess of L-(+)-lactic acid.
6. The consumer product of claim 4 comprising a liquid mixture comprising MLL.
7. The consumer product of claim 1 wherein the liquid mixture comprises a coolant selected from the group consisting of menthol, isopulegol, menthyl lactate, WS-3, WS-23, WS-5, monomenthyl glutarate, monomenthyl succinate, and mixtures thereof.
8. A liquid cooling composition comprising 0.1 ppm to 5 wt. % of at least one lactoyl ester of menthyl lactate; and one or more coolants selected from the group consisting of WS-3, WS-23, WS-5, monomenthyl glutarate, monomenthyl succinate, and mixtures thereof.
9. The composition of claim 8 wherein the lactoyl ester is MLL.
10. The composition of claim 9 wherein the MLL is prepared by reacting l-menthol and an excess of L-(+)-lactic acid.
11. The consumer product of claim 1 , wherein the coolant is a menthoxypropanediol.