IP Library Patent Application 12808025
Patent Application
App. No. 12/808,025

SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHY-DRO-5H-PYRROLO[3,4-B]PYRAZINE

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Quick Facts
Patent No.
US None
App. No.
12/808,025
Abstract

Novel mesylate, (R)-mandelate, succinate, citrate, fumarate, D-malate, D-tartrate, sulfate and L-tartrate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided.

Claims (23)

1 . A salt of zopiclone chosen from a mesylate, (R)-mandelate, succinate, citrate, fumarate, D-malate, D-tartrate, sulfate and L-tartrate salt.

2 . A salt of eszopiclone chosen from a mesylate, (R)-mandelate, succinate, citrate, fumarate, D-malate, D-tartrate, sulfate and L-tartrate salt.

3 . A salt according to claim 1 of formula

4 . A salt according to claim 2 of formula

5 . A salt according to claim 1 of formula

6 . A salt according to claim 2 of formula

7 . A salt according to claim 1 of formula

8 . A salt according to claim 2 of formula

9 . A salt according to claim 1 of formula

10 . A salt according to claim 2 of formula

11 . A salt according to claim 1 of formula

12 . A salt according to claim 2 of formula

13 . A salt according to claim 1 of formula

14 . A salt according to claim 2 of formula

15 . A salt according to claim 1 of formula

16 . A salt according to claim 2 of formula

17 . A salt according to claim 1 of formula

18 . A salt according to claim 2 of formula

19 . A salt according to claim 1 of formula

20 . A salt according to claim 2 of formula

21 . A pharmaceutical dosage form comprising the salt of claim 1 and a pharmaceutically acceptable carrier.

22 . A composition formed by reacting racemic or enantioenriched 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine and an acid chosen from methanesulfonic acid, (R)-mandelic acid, succinic acid, citric acid, fumaric acid, D-malic acid, D-tartartic acid, L-tartaric acid and sulfuric acid.

23 .- 31 . (canceled)

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 28, 2013
From: MOUSAW, PATRICK
To: SUNOVION PHARMACEUTICALS INC.
Reel/Frame 030492/0087 →
CHANGE OF NAME Recorded Jan 26, 2011
From: SEPRACOR INC.
To: SUNOVION PHARMACEUTICALS INC.
Reel/Frame 025699/0042 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2010
From: WILKINSON, H. SCOTT; HSIA, RICHARD; MISRA, TUSHAR; SARANTEAS, KOSTAS
To: SEPRACOR INC.
Reel/Frame 024969/0537 →