The present disclosure relates to compositions and methods for treating, preventing and improving the condition and aesthetic appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, where the compositions include natural plant constituents which increase expression levels genes, collagen replacement and retention, and cell proliferation of epidermis and dermis associated with the dermatological signs of aging. The compositions of the invention are topically applied to the skin, or are delivered by directed means to a site in need thereof, once daily in an amount effective in improving the condition and aesthetic appearance of skin.
1. A method of treating wrinkles and/or fine lines by increasing the proliferation of fibroblasts and keratinocytes in skin, comprising topically applying to skin having wrinkles and/or fine lines a topical composition comprising (a) a water and ethanol extract from a vine of the Tiliacora triandra Diels plant; and (b) a cosmetically, dermatologically, pharmaceutically, or physiologically acceptable vehicle; wherein the extract is obtained by extraction with a solvent mixture comprising from about 10% by volume to about 90% by volume ethanol and from about 10% to about 90% by volume water; and such that proliferation of fibroblasts and keratinocytes in said skin is increased.
2. The method according to claim 1 , wherein the skin is sensitive skin.
3. The method according to claim 1 , wherein the composition is topically applied at least once daily for at least one week.
4. The method according to claim 1 , wherein the extract is present in an amount about 0.0001 wt % to about 90 wt % based on the total weight of the composition.
5. The method according to claim 4 , wherein the extract is present in an amount of from about 0.01 wt % to about 10 wt % of the total weight of the composition.