Ophthalmic compositions comprising povidone-iodine
View Patent ↗A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g. corneal abrasion, postoperative prophylaxis, post-LASIK/LASEK prophylaxis). Additionally the solution is effective in the prevention of infection and inflammation in the post-operative ophthalmic patient.
1. A composition comprising a mixture of
a) povidone-iodine in a concentration of about 10% by weight, and
b) a steroid, wherein the steroid is dexamethasone, and wherein, after a period of one month after mixing the steroid and povidone-iodine to form the composition, the steroid concentration is at least 90% of the steroid starting concentration.
2. A composition comprising a mixture of
a) povidone-iodine, wherein the povidone-iodine is at a concentration selected from the group consisting of about 2.0% by weight and about 4% by weight by weight; and
b) a steroid, wherein the steroid is dexamethasone, and wherein, after a period of one month after mixing the steroid and povidone-iodine to form the composition, the steroid concentration is at least 90% of the steroid starting concentration.