IP Library Granted Patent US 8,871,727
Granted Patent B2
US 8,871,727 · App. 12/816,400 · Granted Oct 28, 2014

Ectoparasiticidal methods and formulations

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Quick Facts
Patent No.
US 8,871,727
App. No.
12/816,400
Granted
Oct 28, 2014
Kind
B2
Abstract

Provided are novel methods and formulations for topically controlling ectoparasite infestations in animals using spinetoram or a pharmaceutically acceptable salt thereof.

Claims (14)

1. A method of controlling ectoparasite infestations of an animal which comprises topically administering a topical liquid pharmaceutical composition comprising an effective amount of spinetoram or a pharmaceutically acceptable salt thereof to said animal, wherein said animal is a companion animal, said ectoparasite is fleas, and said administration is carried out no more than every two weeks.

2. The method of claim 1 wherein said companion animal is a dog.

3. The method of claim 1 wherein said administration is spot-on, plunge or spray dipping, jetting with a hand held spray or in a race, or as a back-line spray or pour-on.

4. The method of claim 1 wherein said administration is carried out no more than monthly.

5. The method of claim 1 wherein said effective amount is 10 to 350 mg/kg of body weight of said animal.

6. The method of claim 1 wherein said flea is Ctenocephalides felis.

7. The method of claim 1 wherein said spinetoram or pharmaceutically acceptable salt is spinetoram.

8. The method of claim 1 wherein said companion animal is a cat.

9. A method for controlling flea infestations of an animal being a dog or cat which comprises topically administering a topical liquid pharmaceutical composition comprising an effective amount of spinetoram or a pharmaceutically acceptable salt thereof to said dog or cat, wherein said effective amount is 10 to 350 mg/kg of body weight of said dog or cat, and said administration is carried out no more than every two weeks.

10. The method of claim 9 wherein said flea is Ctenocephalides felis.

11. The method of claim 9 wherein said administration is carried out no more than monthly.

12. The method of claim 9 wherein said spinetoram or pharmaceutically acceptable salt is spinetoram.

13. The method of claim 9 wherein said animal is a dog.

14. The method of claim 9 wherein said animal is a cat.

Assignments (4)
ASSIGNMENT OF SECURITY INTEREST IN PATENT RIGHTS, RECORDED ON AUGUST 3, 2020, AT REEL/FRAME 053388/0967 Recorded Dec 3, 2025
From: GOLDMAN SACHS BANK USA, AS RETIRING COLLATERAL AGENT
To: JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT
Reel/Frame 073816/0021 →
SECURITY INTEREST Recorded Aug 3, 2020
From: ELANCO US INC.
To: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
Reel/Frame 053388/0967 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 23, 2018
From: ELI LILLY AND COMPANY
To: ELANCO US INC.
Reel/Frame 044700/0489 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2010
From: MEYER, JEFFERY ALAN; WHITE, WILLIAM HUNTER; WINKLE, JOSEPH RAYMOND
To: ELI LILLY AND COMPANY
Reel/Frame 024546/0622 →