IP Library Granted Patent US 8,289,512
Granted Patent B2
US 8,289,512 · App. 12/819,449 · Granted Oct 16, 2012

Devices and systems including a boost device

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Quick Facts
Patent No.
US 8,289,512
App. No.
12/819,449
Granted
Oct 16, 2012
Kind
B2
Abstract

A device for mass spectroscopy comprising a chamber configured to provide an atomization source, a boost device configured to provide radio frequency energy to the chamber, and a mass analyzer in fluid communication with the chamber and configured to separate species based on mass-to-charge ratios is disclosed. In certain examples, a boost device may be used with a flame or plasma to provide additional energy to a flame or plasma to enhance desolvation, atomization, and/or ionization.

Claims (29)

1. A device for mass spectroscopy comprising:

a chamber configured to provide an atomization source comprising a flame;

an energy delivery mechanism configured to provide radio frequency energy to sustain the atomization source comprising the flame in the chamber;

a boost device configured to provide additional radio frequency energy to the flame in the chamber; and

a mass analyzer in fluid communication with the chamber and configured to separate species based on mass-to-charge ratios.

2. The device of claim 1 , in which the mass analyzer is selected from the group consisting of a scanning mass analyzer, a magnetic sector analyzer, a quadrupole mass analyzer, and an ion trap analyzer.

3. The device of claim 1 , further comprising a detection device in fluid communication with the mass analyzer.

4. The device of claim 3 , in which the detection device is selected from the group consisting of an electron multiplier and a Faraday cup.

5. The device of claim 3 , further comprising a processing device in electrical communication with the detection device.

6. The device of claim 5 , in which the processing device is configured to access a database.

7. The device of claim 1 , in which the energy delivery mechanism comprises at least one plate electrode.

8. The device of claim 1 , in which the boost device is configured to provide the additional radio frequency energy in a pulsed mode or a continuous mode.

9. The device of claim 1 , in which the boost device is configured to provide the additional radio frequency energy at a frequency of about 25 MHz to about 50 MHz.

10. The device of claim 1 , in which the boost device is configured to provide the additional radio frequency energy at a power of about 100 Watts to about 2,000 Watts.

11. The device of claim 1 , further comprising a second chamber in fluid communication with the chamber comprising the atomization source.

12. The device of claim 11 , in which the second chamber further comprises a boost device configured to provide radio frequency energy to at least a portion of the second chamber.

13. The device of claim 12 , in which the boost device of the second chamber is configured to provide radio frequency energy of about 25 MHz to about 50 MHz and to provide radiofrequencies at a power of about 100 Watts to about 2,000 Watts.

14. The device of claim 12 , in which the second chamber is in fluid communication with a vacuum pump configured to draw sample from the first chamber into the second chamber.

15. The device of claim 12 , in which the second chamber further comprises an interface comprising an orifice for introducing sample into the second chamber.

16. The device of claim 15 , in which the interface is configured to introduce sample from the first chamber into the second chamber so that the sample is diluted by less than about 15:1 with carrier gas.

17. A device for mass spectroscopy comprising:

a first chamber configured to provide an atomization source comprising a flame;

an energy delivery mechanism configured to provide radio frequency energy to sustain the atomization source comprising the flame in the chamber;

a second chamber in fluid communication with the first chamber;

a boost device configured to provide radio frequency energy to the second chamber; and

a mass analyzer in fluid communication with the second chamber and configured to separate species based on mass-to-charge ratios.

18. The device of claim 17 , in which the mass analyzer is selected from the group consisting of a scanning mass analyzer, a magnetic sector analyzer, a quadrupole mass analyzer, and an ion trap analyzer.

19. The device of claim 17 , further comprising a detection device in fluid communication with the mass analyzer.

20. The device of claim 17 , in which the energy delivery mechanism comprises at least one plate electrode.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2012
From: PERKINELMER, INC.
To: PERKINELMER HEALTH SCIENCES, INC.
Reel/Frame 028771/0766 →