IP Library › Patent Application 12820572
Patent Application
App. No. 12/820,572

ANTI-ANGIOGENIC COMPOSITIONS AND METHODS OF USE

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Patent No.
US None
App. No.
12/820,572
Abstract

The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.

Claims (21)

1 - 9 . (canceled)

10 . A composition, comprising:

(a) paclitaxel; and

(b) a polymeric carrier which comprises poly (lactide-co-glycolide);

wherein the composition is in the form of a pellet.

11 . A composition, comprising:

(a) paclitaxel; and

(b) a polymeric carrier which comprises poly (lactide-co-glycolide);

wherein the composition is in the form of a slab.

12 . A composition, comprising:

(a) paclitaxel; and

(b) a polymeric carrier which comprises poly (lactide-co-glycolide);

wherein the composition is in the form of a film.

13 . A composition, comprising:

(a) paclitaxel; and

(b) a polymeric carrier which comprises poly (lactide-co-glycolide);

wherein the composition is in the form of a spray.

14 . The composition according to any one of claims 10 - 13 , wherein said composition comprises 5-30 micrograms of said paclitaxel.

15 . The composition according to claim 14 , wherein said composition comprises 5 micrograms of said paclitaxel.

16 . The composition according to claim 14 , wherein said composition comprises 10 micrograms of said paclitaxel.

17 . The composition according to claim 14 , wherein said composition comprises 30 micrograms of said paclitaxel.

Assignments (5)
RELEASE OF SECURITY INTEREST : RECORDED AT REEL/FRAME - 049288/0184 Recorded Jan 29, 2021
From: CAPITAL ONE, NATIONAL ASSOCIATION
To: ANGIOTECH PHARMACEUTICALS, INC.
Reel/Frame 055171/0634 →
SECURITY INTEREST Recorded May 26, 2019
From: ANGIOTECH PHARMACEUTICALS, INC.
To: CAPITAL ONE, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 049288/0184 →
RELEASE OF SECURITY INTEREST Recorded Apr 12, 2013
From: WELLS FARGO CAPITAL FINANCE, LLC
To: ANGIOTECH PHARMACEUTICALS, INC.; AMERICAN MEDICAL INSTRUMENTS HOLDINGS, INC.; ANGIOTECH AMERICA, INC.; ANGIOTECH BIOCOATINGS CORP.; ANGIOTECH PHARMACEUTICALS (US), INC.; B.G. SULZLE, INC.; MANAN MEDICAL PRODUCTS, INC.; MEDICAL DEVICE TECHNOLOGIES, INC.; QUILL MEDICAL, INC.; SURGICAL SPECIALTIES CORPORATION; ANGIOTECH INTERNATIONAL HOLDINGS CORP.
Reel/Frame 030211/0479 →
PATENT SECURITY AGREEMENT Recorded May 13, 2011
From: ANGIOTECH PHARMACEUTICALS, INC.; AFMEDICA, INC.; AMERICAN MEDICAL INSTRUMENTS HOLDINGS, INC.; ANGIOTECH AMERICA, INC.; ANGIOTECH BIOCOATINGS CORP.; ANGIOTECH DELAWARE, INC.; ANGIOTECH FLORIDA HOLDINGS, INC.; ANGIOTECH PHARMACEUTICALS (US), INC.; B.G. SULZLE, INC.; MANAN MEDICAL PRODUCTS, INC.; MEDICAL DEVICE TECHNOLOGIES, INC.; NEUCOLL INC.; QUILL MEDICAL, INC.; SURGICAL SPECIALTIES CORPORATION; 0741693 BRITISH COLUMBIA LTD.; ANGIOTECH INTERNATIONAL HOLDINGS, CORP.
To: WELLS FARGO CAPITAL FINANCE, LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 026275/0507 →
PATENT SECURITY AGREEMENT Recorded Aug 19, 2010
From: ANGIOTECH PHARMACEUTICALS, INC.; AFMEDIA, INC.; AMERICAN MEDICAL INSTRUMENTS HOLDINGS, INC.; ANGIOTECH AMERICA, INC.; ANGIOTECH BIOCOATINGS CORP.; ANGIOTECH CAPITAL, LLC; ANGIOTECH PHARMACEUTICALS (US), INC.; B.G. SULZLE, INC.; CRIMSON CARDINAL CAPITAL, LLC; MANAN MEDICAL PRODUCTS, INC.; MEDICAL DEVICE TECHNOLOGIES, INC.; NEUCOLL, INC.; QUILL MEDICAL, INC.; SURGICAL SPECIALITIES CORPORATION; 0741693 B.C. LTD.; 3091796 NOVA SCOTIA COMPANY; ANGIOTECH INTERNATIONAL HOLDINGS, CORP.; ANGIOTECH INVESTMENT PARTNERSHIP
To: WELLS FARGO FOOTHILL, LLC, AS AGENT
Reel/Frame 024861/0219 →