Nutritional composition with prebiotic component
The present disclosure relates to nutritional compositions comprising a prebiotic component for inhibiting adherence of pathogens in the gastrointestinal tract of a subject and to the prebiotic component, which comprises galactooligosaccharide, polydextrose or any mixture thereof. The nutritional compositions of the present disclosure comprise a fat or lipid source, a protein source, and a carbohydrate source comprising an effective amount of the prebiotic component.
1. A method for inhibiting adhesion of pathogens in the gastrointestinal tract of a human subject, comprising administering a nutritional composition which comprises:
(a) a prebiotic component, the prebiotic component comprising a galactooligosaccharide and polydextrose, wherein the combination of the galactooligosaccharide and polydextrose is present in an amount of between about 1.0 g/L and about 10.0 g/L of the nutritional composition; and
(b) at least one long chain polyunsaturated fatty acid in an amount of at least 5 mg/100 kcal of the nutritional composition.
2. The method according to claim 1 , wherein the ratio of polydextrose to galactooligosaccharide is between 9:1 and 1:9, wherein the ratio is determined based on the presence of each component in the nutritional composition in g/L.
3. The method according to claim 1 , further comprising the step of administering at least one probiotic.
4. The method according to claim 3 , wherein the probiotic is selected from the group consisting of Bifidobacteria spp., Lactobacillus spp. and a combination thereof.
5. The method according to claim 1 , wherein the long chain polyunsaturated fatty acid is selected from the group consisting of docosahexaenoic acid, arachidonic acid, and a combination thereof.
6. The method according to claim 1 , wherein the nutritional composition further comprises
a fat or lipid source; and
a protein source.
7. The method according to claim 6 , wherein the nutritional composition is an infant formula.
8. The method according to claim 7 , wherein the nutritional composition is nutritionally complete.
9. The method according to claim 1 , wherein the long chain polyunsaturated fatty acid is selected from the group consisting of docosahexaenoic acid, arachidonic acid, and a combination thereof.
10. The method according to claim 6 , wherein the fat or lipid source is present at a level of about 3 to about 7 g/100 kcal.
11. The method according to claim 6 , wherein the protein source is present at a level of about 1 to about 5 g/100 kcal.
12. The method according to claim 11 , wherein the protein source is selected from the group consisting of whey protein, casein, casein protein, nonfat milk, hydrolyzed protein and combinations thereof.