Intranasal Drug Delivery System

1 - 24 . (canceled)

25 . An intranasal composition comprising

purified water; and

a water-soluble oleoresin capsicum including capsaicin, dihydrocapsaicin, nordihydrocapsaicin, homodihydrocapsaicin, and homocapsaicin,

wherein the oleoresin capsicum is about 0.000001% to 0.0071% by weight of the total weight of the purified water in the system.

26 . The intranasal composition of claim 25 , and further comprising

a drug,

wherein the water-soluble oleoresin capsicum acts as a carrier of the drug and increases the permeability of nasal membranes to the drug.

27 . The delivery system in accordance with claim 26 , wherein the drug is in liquid form.

28 . The intranasal composition of claim 25 , wherein the oleoresin capsicum is between about 1 ppb to 50,000 ppb of the system.

29 . The intranasal composition of claim 25 , wherein capsaicin, dihydrocapsaicin, nordihydrocapsaicin, homodihydrocapsaicins, and homocapsaicin have a heat level of about 100,000 to about 500,000 Scoville units.

30 . The intranasal composition of claim 26 , wherein the drug is homeopathic.

31 . The intranasal composition of claim 25 , wherein the water-soluble oleoresin capsicum comprises between about 67-71% capsaicin, about 20-24% dihydrocapsaicin, about 5-9% nordihydrocapsaicin, about 0.25-2% homodihydrocapsaicin, and about 0.25-2% homocapsaicin.

32 . The intranasal composition of claim 26 , wherein the drug comprises:

0.13% by weight of the total suspension material weight of eucalyptol;

0.10% by weight of the total suspension material weight of feverfew extract; and

0.0027% by weight of the total suspension material weight of peppermint oil, and

wherein the drug delivery system is effective to relieve at least one symptom associated with headaches or migraines.

33 . The intranasal composition of claim 32 , and further comprising:

0.0044% to 0.0047% by weight of the total water weight of water-soluble oleoresin capsicum;

0.08% by weight of the total water weight of rosemary extract;

0.05% by weight of the total water weight of grapefruit seed extract;

3.65% by weight of the total water weight of vegetable glycerin;

0.53% by weight of the total water weight of sea salt;

0.83% by weight of the total water weight of ascorbic acid; and

0.26% by weight of the total water weight of citric acid.

34 . The intranasal composition of claim 26 , wherein the drug comprises 0.13% by weight of the total water weight of eucalyptol; and 0.10% by weight of the total suspension material weight of nettle.

35 . The intranasal composition of claim 34 , and further comprising:

0.0029% to 0.0032% by weight of the total water weight of oleoresin capsicum;

0.09% by weight of the total water weight of rosemary extract;

0.05% by weight of the total water weight of grapefruit seed extract;

3.65% by weight of the total water weight of vegetable glycerin;

0.53% by weight of the total water weight of sea salt;

0.83% by weight of the total water weight of ascorbic acid; and

0.26 by weight of the total water weight of citric acid.

36 . The intranasal composition of claim 26 , and further comprising 0.20% by weight of the total water weight of licorice root extract; and 0.15% by weight of the total water weight of Chinese ginseng.

37 . The intranasal composition of claim 36 , and further comprising:

0.0018% to 0.0021% by weight of the total water weight of the total water weight of oleoresin capsicum;

0.20% by weight of the total water weight of green tea extract;

0.05% by weight of the total water weight of grapefruit seed extract;

3.65% by weight of the total water weight of vegetable glycerin;

0.025% by weight of the total water weight of spearmint oil;

0.83% by weight of the total water weight of ascorbic acid; and

0.26% by weight of the total water weight of citric acid.

38 . The intranasal composition of claim 26 , wherein the drug comprises 0.120% by weight of the total water weight of echinacea extract; 0.13% by weight of the total water weight of eucalyptol; and 0.15% by weight of the total water weight of golden seal extract based on the total water weight of the base.

39 . The intranasal composition of claim 38 , and further comprising:

0.0024% to 0.0027% by weight of the total water weight of oleoresin capsicum;

0.10% by weight of the total water weight of green tea extract;

0.10% by weight of the total water weight of cats claw extract;

0.013% by weight of the total water weight of spearmint oil;

0.05% by weight of the total water weight of grapefruit seed extract;

0.20% by weight of the total water weight of maitake mushroom extract;

3.65% by weight of the total water weight of vegetable glycerin;

0.53% by weight of the total water weight of sea salt;

0.83% by weight of the total water weight of ascorbic acid; and

0.26% by weight of the total water weight of citric acid.

40 . The intranasal composition of claim 26 , wherein the drug comprises 0.10% by weight of the total water weight of marshmallow root extract; and 0.15% by weight of the total water weight of kava extract.

41 . The intranasal composition of claim 40 , and further comprising:

0.0029% by weight of the total water weight of oleoresin capsicum;

0.0-26% by weight of the total water weight of spearmint oil;

0.05% by weight of the total water weight of grapefruit seed extract;

3.65% by weight of the total water weight of vegetable glycerin;

0.83% by weight of the total water weight of ascorbic acid; and

0.26% by weight of the total water weight of citric acid.

42 . The intranasal composition of claim 26 , wherein the drug comprises 0.030% by weight of the total water weight of chaste berry; 0.10% by weight of the total water weight of wild yam root; 0.025% by weight of the total water weight of fennel; and 0.10% by weight of the total water weight of passion flower.

43 . The intranasal composition of claim 42 , and further comprising:

0.0010% to 0.0013% by weight of the total water weight of oleoresin capsicum;

0.30% by weight of the total water weight of don quai extract;

0.025% by weight of the total water weight of spearmint oil;

0.05% by weight of the total water weight of grapefruit seed extract;

3.65% by weight of the total water weight of vegetable glycerin;

0.783% by weight of the total water weight of ascorbic acid; and

0.26% by weight of the total water weight of citric acid.

44 . The intranasal composition of claim 26 , wherein the drug comprises 0.20% by weight of the total water weight of saw palmetto; 0.026% by weight of the total water weight of pygeum africanum; and 0.026% by weight of the total water weight of Chinese ginseng.

45 . The intranasal composition of claim 44 , and further comprising:

0.0023% to 0.0026% by weight of the total water weight of oleoresin capsicum;

0.020% by weight of the total water weight of maitake mushroom extract;

0.010% by weight of the total water weight of pine needle oil;

0.010% by weight of the total water weight of spearmint oil;

0.05% by weight of the total water weight of grapefruit seed extract;

3.65% by weight of the total water weight of vegetable glycerin;

0.783% by weight of the total water weight of ascorbic acid; and

0.26% by weight of the total water weight of citric acid.

46 . A method of delivering a drug to a human, comprising the steps of:

intranasally administering the composition according to claim 25 in combination with a drug,

wherein the water-soluble oleoresin capsicum acts to increase the permeability of nasal membranes to the drug.