Granted Patent
B2
US 8,268,828 · App. 12/852,076 · Granted Sep 18, 2012
Inhibitors of the chemokine receptor CxCR3
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Abstract
This invention is directed to a 3-(amido or sulphamido)-4-(4-substituted-azinyl)benzamide or benzsulphonamide compound as defined herein. The 3-(amido or sulphamido)-(4-substituted-azinyl)benzamide or benzsulphonamide compound is useful as a inhibitor of the chemokine receptor CxCR3, and for preventing or treating a CxCR3 chemokine receptor mediated disease or condition related thereto in a patient in need of such.
Claims (3)
1. A compound selected from the group consisting of the following formulae:
or a pharmaceutically acceptable salt, N-oxide or any combination thereof.
2. A pharmaceutical composition comprising a pharmaceutically acceptable amount of a compound according to claim 1 , and a pharmaceutically acceptable additive.
Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 29, 2011
From: THORPE, DAVID S.; SMRCINA, MARTIN; CABEL, DAGMAR D.
To: SANOFI-AVENTIS
Reel/Frame 026671/0974 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jun 9, 2011
From: THORPE, DAVID S.; SMRCINA, MARTIN; CABEL, DAGMAR D.
To: SANOFI-AVENTIS
Reel/Frame 026415/0193 →