IP Library › Patent Application 12860525
Patent Application
App. No. 12/860,525

DEGRADABLE HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) ACRYLATES AND GELS AND CONJUGATES DERIVED THEREFROM

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
12/860,525
Abstract

A heterobifunctional poly(ethylene glycol) is provided having a hydrolytically degradable linkage, a first terminus comprising an acrylate group, and a second terminus comprising a target such as a protein or pharmaceutical agent or a reactive moiety capable of coupling to a target. Hydrogels can be prepared. The hydrogels can be used as a carrier for a protein or a pharmaceutical agent that can be readily released in a controlled fashion.

Claims (5)

1 . A compound selected from the group consisting of

CH 2 ═CHCO 2 —CH 2 CH 2 —O—(CH 2 CH 2 —O) n —CH 2 CH 2 —O—CH 2 CO 2 CH(CH 3 )CH 2 CONH—CH 2 CH 2 —O—(CH 2 CH 2 —O) n —CH 2 CH 2 —O 2 CCH═CH 2

and

CH 2 ═CHCO 2 —CH 2 CH 2 —O—(CH 2 CH 2 —O) n —CH 2 CH 2 —O—CH 2 CO 2 —CH 2 CH 2 —O—(CH 2 CH 2 —O) n —CH 2 CH 2 —O 2 CCH═CH 2 ,

wherein n is an integer from about 10 to about 2000.