Methods and apparatuses for navigating the subarachnoid space
View Patent ↗Disclosed is a method of navigating a spinal subarchnoid space in a living being, that includes percutaneously introducing a device into the spinal subarachnoid space at an entry location. The device has a first passageway that is sized to slidably receive, and work with, at least a guidewire. The device can be a catheter or a sheath. The method can also include advancing the device within the spinal subarachnoid space at least more than 10 centimeters from the entry location. Alternatively, the method can include advancing the device within the spinal subarachnoid space to facilitate intracranial access with a second device introduced through the first passageway. Also disclosed is a device suited for attachment to a patient's skin, such as a sheath, that includes an elongated member, a skin-attachment apparatus having a flexible skin-attachment flap, and a valve apparatus.
1. A method of achieving intracranial access from an entry location in a spinal subarachnoid space, comprising:
introducing a guidewire into the spinal subarachnoid space;
introducing a device over the guidewire and into the spinal subarachnoid space;
advancing the device from the spinal subarachnoid space into an intracranial subarachnoid space;
introducing a penetration apparatus through the device;
puncturing pia mater using the penetration apparatus;
advancing a detector through the device and through the pia mater; and
placing the detector on or in brain tissue.
2. The method of claim 1 , where the detector is an electroencephalography electrode and the method further comprises:
monitoring electrical activity using the electroencephalography electrode.
3. The method of claim 1 , where the detector is a sensor and the method further comprises:
monitoring a biochemical property using the sensor.
4. The method of claim 3 , where the biochemical property comprises pH, glucose concentration, oxygen tension, carbon dioxide concentration, or sodium concentration.
5. The method of claim 1 , where the detector is a thermal sensor and the method further comprises:
monitoring temperature using the sensor.
6. The method of claim 1 , further comprising:
monitoring neurotransmitter concentration using the detector.
7. The method of claim 1 , where the detector includes an anchoring mechanism.
8. A method of achieving intracranial access from an entry location in a spinal subarachnoid space, comprising:
introducing a guidewire into the spinal subarachnoid space;
introducing a first device over the guidewire and into the spinal subarachnoid space;
advancing the first device from the spinal subarachnoid space into an intracranial subarachnoid space;
introducing a penetration apparatus through the first device;
puncturing pia mater using the penetration apparatus;
advancing a second device through the first device and through the pia mater; and
positioning the second device proximate a brain, a ventricular system, or a cranial nerve.