Multifrequency bioimpedence device and related methods
View Patent ↗Embodiments relate to a device and a method of monitoring and analyzing physiological parameters of a patient. The method includes electrically connecting one or more electrodes with a measurement site of a patient, generating a stimulation signal or signals sufficient to provide multiple stimulation frequencies, multiple waveforms or a combination thereof, measuring a one or more bioimpedance values from the generated signals and analyzing at least one of a fluid bioimpedance contribution, fat bioimpedance contribution or ion bioimpedance contribution within the one or more bioimpedance values sufficient to generate a physiological report.
1. A medical device, comprising:
a measuring interface, located between a device and a measuring site of a patient;
one or more electrodes to generate a frequency sweep stimulation signal, positioned at the measuring interface and in electrical contact with a portion of the patient;
circuitry to measure total bioimpedance values as a result of the stimulation signal at specific frequencies correlating to the frequency sweep; and
a processor system to a quantify a fluid contribution, an ion contribution, and a fat contribution from the measured total bioimpedance values from which a physiological report can be generated, wherein the processor system further identifies whether a measured total bioimpendance is reliable based a non-fluid contribution.
2. The medical device of claim 1 , wherein the measuring interface comprises a patch.
3. The medical device of claim 1 , wherein the circuitry is positioned within the device.
4. The medical device of claim 1 , wherein the circuitry is positioned remotely from the device.
5. The medical device of claim 1 , wherein the processor system is positioned within the device.
6. The medical device of claim 1 , wherein the processor system is positioned remotely from the device.
7. The medical device of claim 1 , wherein the processor system further operates to distinguish muscle tissue from either the fat content or the fluid content or both.
8. The medical device of claim 1 , wherein the frequency sweep includes a frequency where fat is known to resist an electrical current.
9. The medical device of claim 8 , wherein the frequency sweep includes a frequency where fluid is known to interact with an electrical current.
10. The medical device of claim 1 , wherein the frequency sweep stimulation signal is between about 5 kHz and about 1000 kHz, between about 100 kHz and about 800 kHz, or 50 kHz and about 500 kHz.
11. The medical device of claim 1 , wherein identifying whether a measured total bioimpendance is reliable based a non-fluid contribution includes identifying an un-reliable measurement based on a high ion value.
12. A method of monitoring and analyzing physiological parameters of a patient, comprising:
electrically connecting one or more electrodes with a measurement site of a patient;
generating a frequency sweep stimulation signal
measuring, at the measurement site, total bioimpedance values at specific frequencies correlating to the frequency sweep signal;
isolating a fluid bioimpedance contribution, fat bioimpedance contribution and ion bioimpedance contribution from the measured total bioimpedance values, sufficient to generate a physiological report; and
identifying whether a measured total bioimpendance is reliable based a non-fluid contribution.
13. The method of claim 12 , wherein generating comprises providing an electrical current between two or more of the one or more electrodes.
14. The method of claim 12 , wherein the frequency sweep includes at a frequency where fat is known to resist an electrical current.
15. The method of claim 14 , wherein the frequency sweep includes frequency where fluid is known to interact with an electrical current.
16. The method of claim 12 , wherein the frequency sweep stimulation signal is between about 5 kHz and about 1000 kHz.
17. The method of claim 12 , wherein the frequency sweep stimulation signal is between about 100 kHz and about 800 kHz.
18. The method of claim 12 , wherein the frequency sweep stimulation signal is between about 50 kHz and about 500 kHz.
19. The method of claim 12 , wherein identifying whether a measured total bioimpendance is reliable based a non-fluid contribution includes identifying an un-reliable measurement based on a high ion value.
20. The method of claim 17 , wherein identifying whether a measured total bioimpendance is reliable based a non-fluid contribution includes identifying an un-reliable measurement based on a high ion value.