Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor

1. A method for treating oral mucositis induced by an anti-tumor agent in a mammalian subject, which comprises administering a pharmaceutically effective amount of (−)-7-{(2R,4aR,5R,7aR)-2-[(3S)-1,1-difluoro-3-methylpentyl]-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl}heptanoic acid to the subject in need thereof, wherein the subject is receiving the anti-tumor agent that is selected from the group consisting of an alkylating agent, an antimetabolite, an antibiotic, a plant alkaloid, a molecular targeting drug, a hormone, a platinum complex, an antisense, an antibody and RNAi,

wherein the molecular targeting drug is selected from the group consisting of imatinib, gefinitib, erlotinib, sorafenib, sunitinib, trastuzumab, rituximab, gemtuzumab-ozogamicin, bevacizumab and cetuximab, the hormone is selected from group consisting of prednisolone, diethylstilbestrol and tamoxifen, the antisense is selected from the group consisting of bcl-2 antisense, hsp27 antisense, XIAP antisense, PKC-alpha antisense and hypoxia-induced factor antisense, the antibody is selected from the group consisting of CD20 antibody, Her2 antibody, VEGF antibody and EGFR antibody, and the RNAi is RNAi targeted Ribonucleotide reductase.

2. The method as described in claim 1 , wherein said anti-tumor agent is 5-FU or tegafur.

3. The method as described in claim 1 , wherein said anti-tumor agent is cisplatin.

4. The method as described in claim 1 , wherein the oral mucositis is stomatitis.

5. The method as described in claim 1 , wherein the anti-tumor agent is selected from the group consisting of an alkylating agent, an antimetabolite, an antibiotic and a plant alkaloid.