IP Library Granted Patent US 8,785,188
Granted Patent B2
US 8,785,188 · App. 12/887,039 · Granted Jul 22, 2014

Method to formulate T-cells

Inventor: Michael Har-Noy (Jerusalem, IL)
Assignee: Immunovative Therapies, Ltd.
C12N5/0636C12N2531/00A61K2039/57A61K2039/5154C12N2501/515C12N2533/40C12N2501/51
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Quick Facts
Patent No.
US 8,785,188
App. No.
12/887,039
Granted
Jul 22, 2014
Kind
B2
Abstract

A method for formulating T-cells for use as a medicant comprises activating the T-cells by incubating the T-cells in a nutrient culture media with an activating agent. The T-cells together with the activating agent are suspended in a media suitable for infusion. The activated T-cells are packaged together with the activating agent in a container suitable for administration to a patient.

Claims (7)

1. A method to formulate T-cells for use as a medicant comprising:

activating the T-cells by incubating the T-cells in a nutrient culture media with an activating agent;

suspending the activated T-cells together with the activating agent in a media suitable for infusion; and

packaging the activated T-cells together with the activating agent in a container suitable for administration to a patient.

2. The method of claim 1 wherein the T-cells are Th1 cells.

3. The method of claim 1 wherein the media suitable for infusion is PlasmaLyteA supplemented with human serum albumin.

4. The method of claim 1 wherein the container is a syringe.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE CORRECT THE ADDRESS OS THE ASSIGNEE PREVIOUSLY RECORDED AT REEL: 050489 FRAME: 0245. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 28, 2020
From: HAR-NOY, MICHAEL
To: MIRROR BIOLOGICS, INC.
Reel/Frame 052915/0513 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNOR'S NAME FROM IMMUNOVATIVE THERAPIES, LTD. TO MICHAEL HAR-NOY ON THE ORIGINAL COVER SHEET PREVIOUSLY RECORDED ON REEL 050489 FRAME 0245. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 2, 2019
From: HAR-NOY, MICHAEL
To: MIRROR BIOLOGICS, INC.
Reel/Frame 050610/0633 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 25, 2019
From: IMMUNOVATIVE THERAPIES, LTD.
To: MIRROR BIOLOGICS, INC.
Reel/Frame 050489/0245 →
RESCISSION Recorded Sep 12, 2019
From: HAR-NOY, MICHAEL
To: HAR-NOY, MICHAEL
Reel/Frame 050467/0081 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2010
From: HAR-NOY, MICHAEL
To: IMMUNOVATIVE THERAPIES LTD.
Reel/Frame 025085/0709 →
Continuity (8)
Continuation 12173330 · Jul 15, 2008
Division 11069010 · Mar 1, 2005
Continuation In Part 10838454 · May 4, 2004
Provisional Application 60549032 · Mar 1, 2004
Provisional Application 60547966 · Feb 26, 2004
Provisional Application 60545450 · Feb 18, 2004
Provisional Application 60470171 · May 13, 2003
Related Publication 20110028912A1 · Feb 3, 2011