Synthesis of porphyrin nanostructures
View Patent ↗The present disclosure generally relates to self-assembly methods for generating porphyrin nanostructures. For example, in one embodiment a method is provided that includes preparing a porphyrin solution and a surfactant solution. The porphyrin solution is then mixed with the surfactant solution at a concentration sufficient for confinement of the porphyrin molecules by the surfactant molecules. In some embodiments, the concentration of the surfactant is at or above its critical micelle concentration (CMC), which allows the surfactant to template the growth of the nanostructure over time. The size and morphology of the nanostructures may be affected by the type of porphyrin molecules used, the type of surfactant used, the concentration of the porphyrin and surfactant the pH of the mixture of the solutions, and the order of adding the reagents to the mixture, to name a few variables.
1. A method for producing porphyrin nanostructures, comprising:
preparing a porphyrin solution comprising porphyrin molecules and a surfactant solution comprising surfactant molecules, wherein the porphyrin solution and the surfactant solution are aqueous solutions having different pH;
combining the porphyrin solution and the surfactant solution to neutralize the solutions and produce a porphyrin-surfactant mixture, wherein the concentration of the surfactant molecules within the porphyrin-surfactant mixture is above the critical micelle concentration of the surfactant molecules; and
agitating the porphyrin-surfactant mixture for an amount of time to produce a plurality of porphyrin nanostructures.
2. The method of claim 1 , wherein the porphyrin solution comprises an acidic aqueous solution and the surfactant solution comprises a basic aqueous solution, and the porphyrin-surfactant mixture is at a pH above 7.
3. The method of claim 1 , wherein the porphyrin solution comprises an acidic aqueous solution and the surfactant solution comprises a basic aqueous solution, and the porphyrin-surfactant mixture is at a pH below 7.
4. The method of claim 1 , wherein the porphyrin solution comprises a basic aqueous solution and the surfactant solution comprises an acidic aqueous solution, and the porphyrin-surfactant mixture is at a pH above 7.
5. The method of claim 1 , wherein the porphyrin solution comprises a basic aqueous solution and the surfactant solution comprises an acidic aqueous solution, and the porphyrin-surfactant mixture is at a pH below 7.
6. The method of claim 1 , comprising removing at least a portion of the surfactant molecules from the porphyrin-surfactant mixture after agitating the porphyrin-surfactant mixture for the amount of time to isolate the plurality of porphyrin nanostructures from the portion of the surfactant molecules.
7. The method of claim 1 , wherein agitating the porphyrin-surfactant mixture for an amount of time comprises self-assembling at least a portion of the porphyrin molecules within a micelle formed by at least a portion of the surfactant molecules.
8. The method of claim 1 , wherein the molar ratio of surfactant molecules to porphyrin molecules is at least about 3 to 1.
9. The method of claim 1 , wherein the plurality of porphyrin nanostructures comprise 1D nanostructures.
10. The method of claim 1 , wherein the plurality of porphyrin nanostructures comprise 2D nanostructures.
11. The method of claim 1 , wherein the plurality of porphyrin nanostructures comprise 3D nanostructures.
12. The method of claim 1 , wherein the porphyrin molecules are each coordinated to a metal.
13. The method of claim 12 , wherein the metal comprises Zn, Fe, Cu, or Pt.
14. The method of claim 1 , wherein the porphyrin molecules comprise more than one type of porphyrin.
15. The method of claim 1 , wherein the porphyrin molecules are not coordinated to a metal.
16. The method of claim 1 , wherein the surfactant molecules comprise an anionic surfactant, a non-ionic surfactant, a cationic surfactant, or any combination thereof.
17. The method of claim 1 , wherein the porphyrin molecules comprise a porphine inner core and at least two pendant moieties capable of coordinating to a metal.
18. The method of claim 1 , comprising adjusting the pH of the porphyrin-surfactant mixture after the porphyrin solution and the surfactant solution are combined.