Compositions comprising an anti-inflammatory blend
View Patent ↗The present invention relates to a composition comprising an NFκB-inhibitor and an anti-inflammatory compound. The anti-inflammatory compound is not an NFκB-inhibitor and has an IC50 of about 70 μg/ml or less.
1. A composition comprising:
an NFκB-inhibitor selected from the group consisting of substituted resorcinols, (E)-3-(4-methylphenylsulfonyl)-2-propenenitrile, extracts of Paulownia tomentosa wood, and combinations thereof; and
an anti-inflammatory compound that is not an NFκB-inhibitor and has an IC50 of about 70 μg/ml or less, wherein the NFκB-inhibitor and the anti-inflammatory compound are present in a weight ratio from about 1:10 to about 10:1.
2. A composition comprising:
an NFκB-inhibitor selected from the group consisting of substituted resorcinols; and
an anti-inflammatory compound selected from the group consisting of Phellodendron amurense cortex extract (PCE), feverfew ( Tanacetum parthenium ), ginkgo ( Ginkgo Biloba ), cotinus ( Cotinus coggygria ), goji berry ( Lycium barbarum ), milk thistle extract ( Silybum marianum ), amaranth oil ( Amaranthus cruentus ), pomegranate ( Punica granatum ), yerba mate ( Ilex paraguariensis leaf extract), white lily flower extract ( Lilium Candidum ), olive leaf extract ( Olea europaea ), phloretin (apple extract), and combinations thereof, wherein the substituted resorcinol is free of phenyl moieties.
3. A composition comprising:
an NFκB-inhibitor selected from the group consisting of substituted resorcinols; and
an anti-inflammatory compound selected from the group consisting of Phellodendron amurense cortex extract (PCE), feverfew ( Tanacetum parthenium ), ginkgo ( Ginkgo Biloba ), cotinus ( Cotinus coggygria ), goji berry ( Lycium barbarum ), milk thistle extract ( Silybum marianum ), amaranth oil ( Amaranthus cruentus ), pomegranate ( Punica granatum ), yerba mate ( Ilex paraguariensis leaf extract), white lily flower extract ( Lilium Candidum ), olive leaf extract ( Olea europaea ), phloretin (apple extract), and combinations thereof, wherein the substituted resorcinol is 4-hexyl resorcinol.
4. A composition comprising:
an NFκB-inhibitor selected from the group consisting of substituted resorcinols; and
an anti-inflammatory compound selected from the group consisting of Phellodendron amurense cortex extract (PCE), feverfew ( Tanacetum parthenium ), ginkgo ( Ginkgo Biloba ), cotinus ( Cotinus coggygria ), goji berry ( Lycium barbarum ), milk thistle extract ( Silybum marianum ), amaranth oil ( Amaranthus cruentus ), pomegranate ( Punica granatum ), yerba mate ( Ilex paraguariensis leaf extract), white lily flower extract ( Lilium Candidum ), olive leaf extract ( Olea europaea ), phloretin (apple extract), and combinations thereof, wherein the NFκB-inhibitor and the anti-inflammatory compound are present in a weight ratio from about 1:10 to about 10:1.