Multiple biopsy apparatus and related method of use
View Patent ↗An endoluminal biopsy device is provided with a proximal actuation mechanism attached to a distal sampler by at least one elongate member. The distal sampler includes a distal inner portion defining a plurality of chambers, each configured to receive a tissue sample, and a distal outer portion defining a cutting mechanism opening having a cutting edge adjacent the cutting mechanism opening. The distal outer portion is configured so that, when the cutting mechanism opening aligns with one of the plurality of chambers, the distal outer portion covers the remaining chambers. A related method for the use of such an endoluminal biopsy device also is provided.
1. An endoluminal device comprising:
a distal inner portion having a longitudinal axis and defining a plurality of chambers configured to receive a tissue sample;
a distal outer portion defining an opening and a cutting edge adjacent the opening, the distal outer portion being rotatably movable relative to the distal inner portion; and
a plurality of vacuum lumens, wherein at least one of the plurality of chambers is fluidly connected to at least one of the plurality of vacuum lumens at an interface, wherein a diameter of the at least one vacuum lumen at the interface is smaller than a diameter of the at least one chamber;
wherein each of the plurality of chambers has an opening that faces a direction transverse to the longitudinal axis; and
wherein the opening of the distal outer portion is configured to rotate over and expose one of the plurality of chambers when the distal outer portion covers another chamber of the plurality of chambers.
2. The device of claim 1 , wherein the plurality of chambers each has an opening that faces a direction transverse to the longitudinal axis.
3. The device of claim 1 , wherein the plurality of chambers are spaced about a periphery of the distal inner portion.
4. The device of claim 3 , wherein the plurality of chambers are spaced every 90 degrees about the periphery of the distal inner portion.
5. The device of claim 1 , wherein the distal inner portion is configured to keep the tissue sample obtained within one of the plurality of chambers separate from tissue samples obtained within a remainder of the plurality of chambers.
6. The device of claim 1 , further comprising a proximal actuation mechanism for controlling movement of the distal outer portion relative to the distal inner portion.
7. An endoluminal device comprising:
a distal inner portion having a longitudinal axis and defining a plurality of chambers configured to receive a tissue sample;
a distal outer portion defining an opening and a cutting edge adjacent the opening, the distal outer portion being rotatably movable relative to the distal inner portion,
wherein each of the plurality of chambers has an opening that faces a direction transverse to the longitudinal axis;
wherein the plurality of chambers are located on a distal face of the distal inner portion; and
wherein the opening of the distal outer portion is configured to rotate over and expose one of the plurality of chambers when the distal outer portion covers another chamber of the plurality of chambers.
8. The device of claim 7 , further comprising a plurality of vacuum lumens, wherein each of the plurality of chambers is fluidly connected to a corresponding one of the plurality of vacuum lumens at an interface, wherein a diameter of each vacuum lumen at the interface is smaller than a diameter of the chamber to which the vacuum lumen is fluidly connected.
9. The device of claim 7 , wherein the distal inner portion is configured to keep the tissue sample obtained within one of the plurality of chambers separate from tissue samples obtained within a remainder of the plurality of chambers.
10. The device of claim 7 , further comprising a proximal actuation mechanism for controlling movement of the distal outer portion relative to the distal inner portion.
11. An endoluminal device comprising:
a distal inner portion having a longitudinal axis and defining at least a first chamber and a second chamber, each of the first and second chambers being configured to receive a tissue sample;
a distal outer portion defining an opening and a cutting edge adjacent the opening, the distal outer portion being rotatably movable relative to the distal inner portion; and
at least a first vacuum lumen and a second vacuum lumen, the first vacuum lumen being fluidly connected to the first chamber, and the second vacuum lumen being fluidly connected to the second chamber,
wherein an opening of the first chamber faces a first direction and an opening of the second chamber faces a second direction, the first direction being perpendicular to the second direction; and
wherein the opening of the distal outer portion is configured to rotate over and expose one of the first and second chambers when the distal outer portion covers another chamber of the first and second chambers.
12. The device of claim 11 , wherein a diameter of the first vacuum lumen is smaller than a diameter of the first chamber, and a diameter of the second vacuum lumen is smaller than a diameter of the second chamber.
13. The device of claim 11 , wherein the openings each faces a direction that is transverse to the longitudinal axis.
14. The device of claim 11 , wherein the first and second chambers are located at a same axial location along the longitudinal axis about a periphery of the distal inner portion, and the distal inner portion is configured to keep the tissue sample obtained within the first chamber separate from another tissue sample located in the second chamber.
15. The device of claim 11 , further comprising a proximal actuation mechanism for controlling movement of the distal outer portion relative to the distal inner portion.