IP Library Granted Patent US 8,334,402
Granted Patent B2
US 8,334,402 · App. 12/899,361 · Granted Dec 18, 2012

Biological buffers with wide buffering ranges

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Quick Facts
Patent No.
US 8,334,402
App. No.
12/899,361
Granted
Dec 18, 2012
Kind
B2
Abstract

Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa's will extend the buffering range, derivatives that result in polyamines that have the same pKa yields a greater buffering capacity. Derivatives that result in zwitterionic buffers improve yield by allowing a greater range of stability.

Claims (18)

1. A biological buffer of the following structure:

Where n is from 2 to 8 and A is chosen from the following: —CH 3 , —CH 2 CH 3 , —OH, —CH 2 COOH.

2. A biological buffer of claim 1 where n=2 and A is —CH 3 .

3. A biological buffer of the following structure:

4. A biological buffer of the following structure:

5. A gas scrubbing or buffering amine of the following structure:

6. A gas scrubbing or buffering amine of the following structure:

Where A is chosen from —CH 3 , —CH 2 CH 3 , —CH 2 OH, or —H.

7. A biological buffer of the following structure:

Where A is chosen from the group —OH, —CH 3 , or —CH 2 CH 3 , and M + is a cation.

8. A biological buffer of the following structure:

Where A is chosen from the group —H, —OH, —CH 3 , or —CH 2 CH 3 and M + is a cation.

9. A biological buffer of the following structure:

Where n and m are integers independently chosen from 1-3.

10. A biological buffer of the following structure:

where n is an integer from 1 to 3.

11. A biological buffer of claim 10 where n=1.

12. A biological buffer of claim 10 where n=2.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 4, 2020
From: DALY, THOMAS P.
To: TPAT IP LLC
Reel/Frame 052006/0065 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 19, 2015
From: DALY, THOMAS P.
To: TPAT IP LLC
Reel/Frame 037094/0016 →