Precision registration of X-ray images to cone-beam CT scan for image-guided radiation treatment
View Patent ↗A method for precision registration of X-ray images to cone-beam CT scan for image-guided radiosurgery includes acquiring 2-D pre-treatment X-ray images of a region of interest, acquiring a 2-D X-ray image of the region of interest at approximately a time of treatment, registering the 2-D X-ray image with a corresponding 2-D pre-treatment X-ray image to obtain a 2-D registration result at approximately the time of treatment, and converting the 2-D registration result into a 3-D tracking result to track the region of interest.
1. A method, comprising:
acquiring a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient;
acquiring a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest;
registering, using a hardware processor, the first one or more 2-D X-ray images with the second one or more 2-D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient; and
converting, using the hardware processor, the 2-D registration result into a 3-D tracking result to track movement of the region of interest.
2. A method, comprising:
acquiring a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient;
acquiring a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest; and
registering, using a hardware processor, the first one or more 2-D X-ray images with the second one or more 2-D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient, wherein registering the first one or more 2-D X-ray images with the second one or more 2-D X-ray images comprise calculating an in-plane translation, an in-plane rotation and an out-of-plane rotation.
3. The method of claim 1 , further comprising processing the first one or more 2-D X-ray images to extract an image feature for registration with the second one or more 2-D X-ray images.
4. The method of claim 1 , wherein the second one or more 2-D X-ray images is acquired using an X-ray beam source mounted in a gantry structure configured to rotate around the patient in a fixed plane of rotation.
5. A method, comprising:
acquiring a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient;
acquiring a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest; and
registering, using a hardware processor, the first one or more 2-D X-ray images with the second one or more 2-D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient, wherein the first one or more 2-D X-ray images comprises a first pair of projected images of the region of interest, the first pair of projected images including the first projected image.
6. A method, comprising:
acquiring a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient;
acquiring a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest; and
registering, using a hardware processor, the first one or more 2-D X-ray images with the second one or more 2-D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient, wherein the second one or more 2-D X-ray images comprises a second pair of projected images of the region of interest, the second pair of projected images including the second projected image.
7. The method of claim 1 , wherein the first one or more two-dimensional (2-D) X-ray images of a region of interest are pre-treatment images.
8. The method of claim 1 , wherein the second one or more two-dimensional (2-D) X-ray images of a region of interest is acquired at approximately the time of treatment of the patient.
9. A non-transitory computer-readable storage medium containing instructions that when executed on a data processing system causes the system to perform operations, comprising:
acquiring a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient;
acquiring a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest;
registering, using the data processing system, the first one or more 2-D X-ray images with the second one or more 2-D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient; and
converting the 2-D registration result into a 3-D tracking result to track movement of the region of interest.
10. The non-transitory computer-readable storage medium of claim 9 , wherein registering the first one or more 2-D X-ray images with the second one or more 2-D X-ray images comprise calculating an in-plane translation, an in-plane rotation and an out-of-plane rotation.
11. The non-transitory computer-readable storage medium of claim 9 , wherein the operations further comprise processing the first one or more 2-D X-ray images to extract an image feature for registration with the second one or more 2-D X-ray images.
12. The non-transitory computer-readable storage medium of claim 9 , wherein the second one or more 2-D X-ray images is acquired using a X-ray beam source mounted in a gantry structure that rotates around the patient in a fixed plane of rotation.
13. A non-transitory computer-readable storage medium containing instructions that when executed on a data processing system causes the system to perform operations, comprising:
acquiring a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient;
acquiring a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest;
registering, using the data processing system, the first one or more 2-D X-ray images with the second one or more 2-D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient, wherein the first one or more 2-D X-ray images comprises a first pair of projected images of the region of interest, the first pair of projected images including the first projected image.
14. A non-transitory computer-readable storage medium containing instructions that when executed on a data processing system causes the system to perform operations, comprising:
acquiring a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient;
acquiring a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest;
registering, using the data processing system, the first one or more 2-D X-ray images with the second one or more 2-D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient, wherein the second one or more 2-D X-ray images comprises a second pair of projected images of the region of interest, the second pair of projected images including the second projected image.
15. The non-transitory computer-readable storage medium of claim 9 , wherein the first one or more two-dimensional (2-D) X-ray images of a region of interest are pre-treatment images.
16. The non-transitory computer-readable storage medium of claim 9 , wherein the second one or more two-dimensional (2-D) X-ray images of a region of interest is acquired at approximately the time of treatment of the patient.
17. An apparatus, comprising:
an imager to acquire a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient, the imager further to acquire a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest; and
a processor operatively coupled to the imager, the processor to register the first one or more 2-D X-ray images with the second one or more 2- D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient, and to convert the 2-D registration result into a 3 -D tracking result to track movement of the region of interest.
18. The apparatus of claim 17 , wherein the processor is further configured to process the first one or more 2-D X-ray images to extract an image feature for registration with the second one or more 2-D X-ray images.
19. The apparatus of claim 17 , further comprising an X-ray beam source mounted in a gantry structure to rotate around the patient in a fixed plane of rotation, and wherein the second one or more 2-D X-ray images is acquired using the X-ray beam source.
20. The apparatus of claim 17 , wherein the first one or more two-dimensional (2-D) X-ray images of a region of interest are pre-treatment images.
21. The apparatus of claim 19 , wherein the second one or more two-dimensional (2-D) X-ray images of a region of interest is acquired at approximately the time of treatment of the patient.
22. An apparatus, comprising:
an imager to acquire a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient, the imager further to acquire a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest; and
a processor operatively coupled to the imager, the processor to register the first one or more 2-D X-ray images with the second one or more 2- D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient, wherein registering the first one or more 2-D X-ray images with the second one or more 2-D X-ray images comprise calculating an in-plane translation, an in-plane rotation and an out-of- plane rotation.
23. An apparatus, comprising:
an imager to acquire a first one or more two-dimensional (2-D) X-ray images of a region of interest, wherein the first one or more 2-D X-ray images comprises a first projected image of the region of interest of a patient, the imager further to acquire a second one or more 2-D X-ray images of the region of interest, wherein the second one or more 2-D X-ray images comprises a second projected image of the region of interest; and
a processor operatively coupled to the imager, the processor to register the first one or more 2-D X-ray images with the second one or more 2- D X-ray images to obtain a 2-D registration result at approximately a time of treatment of the patient, wherein the second one or more 2-D X-ray images comprises a second pair of projected images of the region of interest, the second pair of projected images including the second projected image.