Use of a neuregulin to treat peripheral nerve injury
View Patent ↗Embodiments of the invention are directed to use of neuregulins to prevent or treat peripheral nerve injury, to attenuate, ameliorate or avoid the loss of peripheral nerve function.
1. A method of treating an erectile dysfunction resulting from a peripheral nerve injury comprising administering an effective amount of a glial growth factor 2 (GGF2) polypeptide comprising the sequence of SEQ ID NO: 1 to a subject at risk of suffering a peripheral nerve injury or to a subject having an existing peripheral nerve injury, wherein the peripheral nerve injury is the result of a surgical procedure.
2. The method of claim 1 , wherein the GGF2 is administered prior to a surgical procedure.
3. The method of claim 1 , wherein the surgical procedure is a prostate cancer surgery.
4. The method of claim 3 , wherein the prostate cancer surgery is a prostatectomy.
5. The method of claim 1 , wherein the subject is at risk of suffering a peripheral nerve injury.
6. The method of claim 1 , wherein the subject has an existing peripheral nerve injury.
7. The method of claim 1 or 2 , wherein the peripheral nerve injury is a cavernous nerve injury.