Compositions comprising a retinoid and an NFkB-inhibitor and their methods of use
View Patent ↗A composition including a retinoid, an NFκB-inhibitor, and a cosmetically-acceptable topical carrier is provided. Methods of treating the skin are also provided.
1. A composition comprising a retinoid, 4-hexyl resorcinol, and a cosmetically-acceptable topical carrier, wherein the amount of retinoid in the composition is no more than 0.075% by weight of the composition and the amount of 4-hexyl resorcinol is no more than about 0.5% by weight of the composition.
2. The composition of claim 1 comprising about 0.1% to about 0.5% by weight of 4-hexyl resorcinol.
3. The composition of claim 1 , wherein said retinoid is retinol.
4. The composition of claim 3 comprising 0.01% to 0.075% by weight retinol.
5. The composition of claim 3 comprising 0.01% to 0.06% by weight retinol.
6. The composition of claim 1 , wherein said retinoid and said NFκB-inhibitor are present in amounts sufficient to provide a % Synergy in CRABPII activation of at least about 15%.