Method of administering an injectable antibiotic to an animal
View Patent ↗A method of administering an antibiotic to an animal in need thereof, including the step of injecting the antibiotic subcutaneously at the junction of a pinna with the cranium of the animal, is disclosed.
1. A method for treating a bacterial infection in an animal in need thereof comprising injection of an effective amount of an antibiotic subcutaneously at the junction of a pinna with the cranium of the animal, wherein the animal is cattle and the injection is caudal to the cervicoauricularis muscles and dorsocaudal to the parotid salivary gland.
2. The method of claim 1 , wherein the injection is within the dorsocaudal half of the junction.
3. The method of claim 1 wherein the antibiotic is selected from the group consisting of procaine penicillin, benzathine penicillin, ceftiofur crystalline free acid, ceftiofur hydrochloride, ampicillin trihydrate, amoxicillin trihydrate, oxytetracycline, erythromycin, tylosin, tilmicosin, florfenicol, enrofloxacin, danofloxacin, and premafloxacin.
4. The method of claim 1 wherein the antibiotic is crystalline ceftiofur free acid of formula I
which is 7-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino)acetamido]-3-[(fur-2-ylcarbonyl)thiomethyl]-3-cephem-4-carboxylic acid.
5. The method of claim 4 , wherein crystalline ceftiofur free acid is in a sterile oil suspension.
6. The method of claim 5 , wherein the injected volume of the formulation is from about 1 ml to about 15 ml.
7. The method of claim 6 , wherein the antibiotic is injected with a single syringe needle.
8. The method of claim 1 , wherein the bacterial infection is bovine respiratory disease.
9. The method of claim 4 , wherein the amount of ceftiofur crystalline free acid is from about 1.1 to about 8.8 mg/kg of body weight.
10. The method of claim 9 , wherein the amount of ceftiofur crystalline free acid is from about 4.4 to about 6.6 mg/kg of body weight.