Intervertebral implant with movement resistant structure
View Patent ↗An implant unit used in surgery has a body made from osteogenic implantable material and including an implant portion and a retaining portion, which is coupled to and extends transversely to the implant portion. The retaining portion is attached to the sidewall of the adjoining vertebral body or mammal bone to prevent displacement of the implant portion relative to the vertebral body or mammal bone and to accelerate fusion therebetween.
1. An implant comprising a body made entirely from osteogenic implantable material and including an implant portion and a retaining portion coupled to and extending transversely to the implant portion, the retaining and implant portions are selectively demineralized to expose collagen fibers to provide the selectively demineralized retaining and implant portions with improved osteoinductive characteristics, wherein the exposed collagen fibers are bound by reinforcing fibers.
2. The implant according to claim 1 , wherein the retaining and implant portions are integrally coupled to one another to form a monolithic, one-piece body.
3. The implant according to claim 1 , wherein the retaining and implant portions are detachably coupled.
4. The implant according to claim 1 , wherein the osteogenic implantable material is selected from the group consisting of mammalian bone including bone particles, bone powder, bone chips, or a bone composite comprising the bone tissue distributed in a polymeric binder and least one biologically active component, medicinal agents and drugs and/or combinations thereof.
5. An implant unit for repairing a vertebral segment or segments or a bone repair site in mammalian comprising:
an implant portion extending in an insertion plane and juxtaposed with surfaces to be repaired; and
a retaining portion extending transversely to the insertion plane of the implant portion attachable to a sidewall of at least one vertebral body or a mammalian bone, the retaining and implant portions being made of osteogenic implantable material and being coupled to one another so that during the period of repair the retaining portion substantially prevents displacement of the implant unit relative to the surface to be repaired and to carry loads over an intervertebral space or the mammalian bone, the retaining and implant portions are selectively demineralized to expose collagen fibers to provide the selectively demineralized retaining and implant portions with improved osteoinductive characteristics, wherein the exposed collagen fibers are bound by reinforcing fibers.
6. The implant unit according to claim 5 , wherein at least one fastener extends through the retaining portion of the implant into the sidewall to secure the retaining portion to the sidewall.
7. The implant unit according to claim 6 , wherein the retaining portion has at least one hole that has an oblong shape, traversed by the at least one fastener so as to allow controlled displacement of the implant unit relative to the at least one fastener to obtain a desired position of the implant unit before tightening the at least one fastener.
8. The implant unit according to claim 5 , wherein the implantable osteogenic material is obtained from bone tissue.
9. The implant unit according to claim 8 , wherein the bone tissue is selected from the group consisting of bone particles, bone powder, bone chips, and/or a combination of these, and/or a bone composite comprising bone tissue distributed in a polymeric binder and may contain at least one biologically active component, medicinal agents and/or drugs.
10. The implant unit according to claim 9 , wherein the bone tissue is selected from long mammalian bones containing a medullary canal defining an opening in the implant portion, the open space may be filled with material selected from demineralized bone powder and/or a cancellous bone plug.
11. The implant unit according to claim 9 , wherein the implant portion has a continuous peripheral wall, which is provided with a polygonal shape or an annular shape, and/or a discontinuous C-shaped or V-shaped peripheral wall.
12. The implant unit according to claim 11 , wherein the peripheral wall has upper and lower surfaces at least one of which may be textured.
13. The implant unit according to claim 12 , wherein the at least one textured surface has ridges, serrations, or knurling to enhance engagement with the fractured surfaces of the bone and/or adjacent vertebral bodies.
14. The implant unit according to claim 12 , wherein at least one of the upper and lower surfaces has a ledge defining portions of the at least one surface extending on different levels.
15. The implant unit according to claim 5 , wherein the retaining portion includes a transverse member with a single wing extending in one lateral direction perpendicular to the insertion plane or with two wings extending in opposing lateral directions from the insertion plane defined by the implant portion.
16. The implant unit according to claim 15 , wherein the transverse member has a stepwise inner surface facing the sidewall of the bone repair site.
17. The implant unit according to claim 5 , wherein the implant portion and the retaining portion are formed as a monolithic, one-piece body.
18. The implant unit according to claim 17 , wherein the retaining portion has a peripheral surface provided with at least one threaded region to enable engagement of the retaining portion with the sidewall of the bone repair site, the implant portion may be provided with a respective thread to facilitate rotational insertion of the implant portion into the bone repair site.
19. The implant unit according to claim 5 , wherein the retaining portion and the implant portion are detachably coupled to one another.
20. The implant unit according to claim 5 , wherein the retaining portion and the implant portion are detachably connected to one another.
21. The implant unit according to claim 20 , wherein the implant portion has a hole extending inwards from a proximal end of the implant portion and having a threaded surface, the retaining portion being provided with an opening and traversed by a screw after the opening and the hole have been aligned, the screw threadedly engages the threaded inner surface to prevent relative displacement between the implant and retaining portions.
22. The implant unit according to claim 21 , wherein the implant portion has an outer threaded surface screwed into a central threaded opening formed in the retaining portion, mating with the threaded surface of the implant portion to prevent relative displacement between the implant and retaining portions.
23. The implant unit according to claim 21 , wherein the implant portion has a flange extending laterally outwards from at least one end of the implant portion and is received in a stepped central opening in the retaining portion and dimensioned so that the flange extends flush with an outer surface of the retaining surface after being inserted into the diseased bone.
24. The implant unit according to claim 5 , wherein the exposed collagen fibers are chemically cross-linked by a cross-linking agent selected from a group consisting of formaldehyde, glutaraldehyde, acetaldehyde, glyoxal pyruvic aldehyde, dialdehyde starch, glycerol polyglycidyl ethers, polyethylene glycol diglycidyl ethers, polyvalent metallic oxides, dicyclohexyl carbodiimide and/or a combination of these.
25. The implant unit according to claim 5 , wherein the implant portion and/or the retaining portion is formed from combinations of cancellous and cortical bone.
26. The implant unit according to claim 5 , wherein the retaining portions have opposing ends spaced laterally outwards from the implant portion and each provided with a respective tab extending generally parallel to the implant portion.
27. The implant unit according to claim 5 , wherein the retaining portion has at least two sections attached to one another by a flexible demineralized connecting portion and each of the at least two portions being integrally formed with a respective implant portion to provide a multilevel joining operation.
28. The implant unit according to claim 27 , wherein the at least two sections, the flexible connecting portion and the implant portions form a monolithic, one-piece structure.