IP Library Granted Patent US 9,155,482
Granted Patent B2
US 9,155,482 · App. 12/920,708 · Granted Oct 13, 2015

Apparatus and method for indicating cardiac output

Inventors: John McCune Anderson (Holywood, GB); Cesar Oswaldo Navarro-Paredes (Newtownabbey, GB); Rebecca DiMaio (Belfast, GB)
Assignee: Heartsine Technologies Limited
A61B5/029A61B5/0535A61N1/39A61N1/3925
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Quick Facts
Patent No.
US 9,155,482
App. No.
12/920,708
Granted
Oct 13, 2015
Kind
B2
Abstract

An apparatus for indicating cardiac output comprises means for monitoring a patient's transthoracic impedance and generating a corresponding impedance signal, and signal processing means for (a) deriving a signal S 1 which is a measure of the average amplitude of the impedance signal, (b) filtering the impedance signal at a plurality of different wavelengths within a predetermined frequency band, (c) for each filter deriving a signal S 2 which is a measure of the average amplitude of the respective filter output, (d) calculating the ratio of the maximum one of the signals S 2 derived from step (c) to the signal S 1 derived from step (a), and (e) using the ratio from step (d) in a decision tree to provide a signal indicating cardiac output or not.

Claims (50)

1. An external defibrillator, comprising:

a processor;

a frequency generator;

a pair of electrodes; and

a non-transitory computer-readable storage medium having instructions stored which, when executed by the processor, cause the processor to perform operations comprising:

signaling the frequency generator to generate an impedance test signal;

when the pair of electrodes are in contact with a patient, applying the impedance test signal to the patient via the pair of electrodes:

receiving an impedance measurement in response to the impedance test signal; repeating the impedance test signal with the patient to acquire a plurality of impedance measurements;

averaging the plurality of impedance measurements over a defined period of time, to yield an average impedance measurements;

filtering each of the plurality of impedance measurements at a plurality of different spaced frequencies within a predetermined band, to yield a plurality of filtered impedance measurements;

averaging each of the plurality of filtered impedance measurements over a defined period of time, to yield a plurality of average filtered impedance measurements;

identifying a maximum average filtered impedance measurement from the plurality of average filtered impedance measurements;

calculating a ratio of the maximum average filtered impedance measurement to the average impedance measurement;

comparing the calculated ratio with a predetermined threshold value to provide a signal indicating the presence or absence of a cardiac output; and providing the signal indicating the presence or absence of the cardiac output to a user.

2. The external defibrillator of claim 1 ,

wherein the threshold value is in a range inclusively comprising 0.25 to 0.75; and

when the calculated ratio exceeds the threshold value, a first signal is provided indicating the presence of a cardiac output; and

when the calculated ratio is below the threshold value, a second signal is provided indicating the absence of a cardiac output.

3. The external defibrillator of claim 2 , the computer-readable storage medium having additional instructions stored which, when executed by the processor, result in operations, comprising:

when the calculated ratio is below the first threshold value,

comparing the calculated ratio with a second threshold value that is lower than the first threshold value; and

when the calculated ratio is less than the second threshold value, providing a distinct signal indicating the absence of a cardiac output.

4. The external defibrillator of claim 3 , wherein the second threshold value is in a range inclusively comprising 0.25 to 0.03.

5. The external defibrillator of claim 1 , wherein the defined period of time is in a range inclusively comprising 1-12 seconds.

6. The external defibrillator of claim 1 , wherein the predetermined frequency band has a bandwidth in a range inclusively comprising 1 to 5 Hz.

7. The external defibrillator of claim 6 , wherein the plurality of different spaced frequencies number at least 6 distinct frequencies within the predetermined frequency band.

8. The external defibrillator of claim 6 , wherein the plurality of different spaced frequencies are consecutively grouped at intervals of a least 0.166 Hz.

9. A method for use with an external defibrillator, comprising:

signaling a frequency generator to generate an impedance test signal;

when a pair of electrodes are in contact with a patient, applying the impedance test signal to the patient via the pair of electrodes;

receiving an impedance measurements in response to the impedance test signal;

repeating the impedance test signal with the patient to acquire a plurality of impedance measurements;

averaging the plurality of impedance measurements over a defined period of time, to yield an average impedance measurements;

filtering each of the impedance measurements at a plurality of different spaced frequencies within a predetermined frequency band, to yield a plurality impedance measurements;

averaging each of the plurality of filtered impedance measurements over a defined period of time, to yield a plurality of average filtered impedance measurements;

indentifying a maximum average filtered impedance measurement from the plurality of average filtered impedance measurements;

calculating a ratio of the maximum average filtered impedance measurement to the average impedance measurement;

comparing the calculated ratio with a predetermined threshold value to provide a signal indicating the presence or absence of a cardiac output; and providing the signal indicating the presence or absence of the cardiac output to a user.

10. A method of claim 9 , wherein the threshold value is in a range inclusively comprising 0.25 to 0.75; and

when the calculated ratio exceeds the threshold value, a first signal is provided indicating the presence of a cardiac output; and

when the calculated ratio is below the first threshold value, a second signal is provided indicating the absence of a cardiac output.

11. The method of claim 10 , comprising:

when the calculated ratio is below the first threshold value,

comparing the calculated ratio with a second threshold value that is lower than the first threshold value; and

when the calculated ratio is less than the second threshold value, providing a signal indicating the absence of a cardiac output.

12. A method of claim 11 , wherein the second threshold value is in range inclusively comprising 0.25 to 0.30.

13. The method of claim 9 , wherein the defined period of time is in a range inclusively comprising 1-12 seconds.

14. The method of claim 9 , wherein the predetermined frequency band has a bandwidth in a range inclusively comprising 1 to 5 Hz.

15. The method of claim 9 , wherein the plurality of different spaced frequencies number at least six distinct frequencies in the predetermined frequency band.

16. The method of claim 9 , wherein the plurality of different spaced frequencies are consecutively grouped at intervals of at least 0.166 Hz.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 26, 2023
From: HEARTSINE TECHNOLOGIES LIMITED
To: STRYKER EUROPEAN OPERATIONS LIMITED
Reel/Frame 065952/0622 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 2, 2010
From: ANDERSON, JOHN MCCUNE; NAVARRO-PAREDES, CESAR; DIMAIO, REBECCA
To: HEARTSINE TECHNOLOGIES LIMITED
Reel/Frame 024931/0612 →
Priority Claims (2)
IE S2008/0163 · Mar 5, 2008 · national
IE S2008/0785 · Sep 26, 2008 · national
Continuity (1)
Related Publication 20110021938A1 · Jan 27, 2011