Method for regulating RF signals in an NMR system and probe head for carrying out the method
A method for regulating radio frequency (RF) signals in a nuclear magnetic resonance (NMR) system, comprising a spectrometer, a control loop, and an NMR probe head with RF components (B E , L E , B K ), wherein the spectrometer comprises a transmitter that transmits RF signals at measuring frequencies with a transmission power (P S ), the NMR probe head contains an RF oscillating circuit, and the RF oscillating circuit comprises an RF coil (L E ), is characterized in that the control loop controls the duration and/or the phase and/or the power of the transmitted RF signals. Measurement of a parameter is performed by means of the NMR probe head, via which parameter the current in or the voltage across one of the RF components (B E , L E , B K ) can be determined, and the transmission powers (P S ) and/or the phases and/or the duration of the RF signals are regulated in dependence on the measured parameter. Any occurring losses can thereby be compensated for without reducing the pulse duration.
1. A method for regulating radio frequency (RF) signals in a nuclear magnetic resonance (NMR) system, the NMR system having a spectrometer, a control loop, and an NMR probe head with RF components, the method comprising the steps of:
a) transmitting, using a transmitter disposed in the NMR spectrometer, RF signals at measuring frequencies and with a transmission power;
b) tuning, using the RF components, an RF oscillating circuit disposed in the NMR probe head to a resonance frequency of a type of nucleus to be investigated;
c) utilizing the RF oscillating circuit to excite nuclear spins In a sample and to receive NMR signals resulting from excitation of those nuclear spins, the RF oscillating circuit having at least one RF coil which is disposed around the sample to emit and receive RF signals;
d) controlling, using the control loop, a duration, phase and/or power of the transmitted RF signals;
e) measuring a parameter using the NMR probe head;
f) determining, using the parameter measured In step e), a current in or a voltage across one of the RF components;
and
g) regulating transmission powers, phases and/or durations of the RF signals in dependence on the parameter measured in step e), wherein the control loop limits the transmission power, maximum permissible current and/or voltage values being determined in at least one of the RF components.
2. The method of claim 1 , wherein a Q-value of the RF oscillating circuit and/or an impedance adjustment of the RF oscillating circuit to a transmission line are measured as the parameter.
3. The method of claim 1 , wherein a pulse duration of an RF pulse with desired pulse angle is measured as the parameter.
4. The method of claim 3 , wherein the pulse duration is determined by detecting at least one NMR signal by means of the NMR spectrometer.
5. The method of claim 4 , wherein an initial value of a transmitting coil is selected for the transmission power, wherein an RF pulse with the initial value of the transmission power is irradiated, the NMR signal is recorded by the NMR spectrometer, the pulse angle of the RF pulse irradiated for generating the NMR signal is determined by means of the recorded NMR signal, and the transmission power of the RF pulse with desired pulse angle and desired pulse duration is determined by the determined pulse angle.
6. The method of claim 1 , wherein a radio frequency H or E field generated by the RF coil is measured as the parameter.
7. The method of claim 6 , wherein transmission powers and/or the phases of the RF signals are adjusted for a duration of a pulse sequence, wherein, during the pulse sequence, several measurements of the radio frequency H or E field generated by the RF coil are carried out.
8. The method of claim 6 , wherein transmission powers and/or the phases of the RF signals are adjusted for a duration of one single pulse, wherein the radio frequency H or E field generated by the RF coil is measured in dependence on time.
9. A nuclear magnetic resonance probe head for performing the method of claim 6 , wherein several RF coils are provided and with a measuring probe for measuring a current in and/or a voltage across the RF coils and/or for measuring an RF field generated by the RF coils, the probe being Inductively coupled to all RF coils.
10. An NMR system comprising the probe head of claim 9 .
11. A method for regulating radio frequency (RF) signals in a nuclear magnetic resonance (NMR) system, the NMR system having a spectrometer, a control loop, and an NMR probe head with RF components, the method comprising the steps of:
a) transmitting, using a transmitter disposed in the NMR spectrometer, RF signals at measuring frequencies and with a transmission power;
b) tuning, using the RF components; an RF oscillating circuit disposed in the NMR probe head to a resonance frequency of a type of nucleus to be investigated;
c) utilizing the RF oscillating circuit to excite nuclear spins in a sample and to receive NMR signals resulting from excitation of those nuclear spins, the RF oscillating circuit having at least one RF coil which is disposed around the sample to emit and receive RF signals;
d) controlling, using the control loop, a duration, phase and/or power of the transmitted RF signals;
e) measuring a parameter using the NMR probe head;
f) determining, using the parameter measured in step e), a current in or a voltage across one of the RF components; and
g) regulating transmission powers, phases and/or durations of the RF signals in dependence on the parameter measured in step e), wherein a Q-value of the RF oscillating circuit and/or an impedance adjustment of the RF oscillating circuit to a transmission line are measured as the parameter.
12. A method for regulating radio frequency (RF) signals in a nuclear magnetic resonance (NMR) system, the NMR system having a spectrometer, a control loop, and an NMR probe head with RF components, the method comprising the steps of:
a) transmitting, using a transmitter disposed in the NMR spectrometer, RF signals at measuring frequencies and with a transmission power;
b) tuning, using the RF components, an RF oscillating circuit disposed in the NMR probe head to a resonance frequency of a type of nucleus to be investigated;
c) utilizing the RF oscillating circuit to excite nuclear spins in a sample and to receive NMR signals resulting from excitation of those nuclear spins, the RF oscillating circuit having at least one RF coil which Is disposed around the sample to emit and receive RF signals;
d) controlling; using the control loop, a duration, phase and/or power of the transmitted RF signals;
e) measuring a parameter using the NMR probe head;
f) determining, using the parameter measured in step e), a current in or a voltage across one of the RF components; and
g) regulating transmission powers, phases and/or durations of the RF signals in dependence on the parameter measured in step e), wherein a radio frequency H or E field generated by the RF coil is measured as the parameter, transmission powers and/or the phases of the RF signals being adjusted for a duration of a pulse sequence and, during the pulse sequence, several measurements of the radio frequency H or E field generated by the RF coil are carried out or transmission powers and/or the phases of the RF signals are adjusted for a duration of one single pulse, wherein the radio frequency H or E field generated by the RF coil is measured in dependence on time.
13. The method of claim 12 , wherein regulation of the transmission power is performed for the duration of one pulse such that the RF pulse shape generated thereby coincides with a previously determined pulse shape.
14. A nuclear magnetic resonance probe head for performing the method of claim 12 , wherein several RF coils are provided and with a measuring probe for measuring a current in and/or a voltage across the RF coils and/or for measuring an RF field generated by the RF coils, the probe being inductively coupled to all RF coils.
15. An NMR system comprising the probe head of claim 14 .