System and method for instrument correction using transmission efficiency
A system and method for providing an instrument response correction based on transmission efficiency. Test data may be acquired at a first operating point. A look-up table may be searched to determine an instrument response correction. This look-up table may comprise a plurality of instrument response corrections, each instrument response correction corresponding to an intensity response of the sample at an operating point. The instrument response correction may then be applied to correct for environmental factors that may affect transmission efficiency. A system may comprise an illumination source, a collection optics, a tunable filter, a detector, a sensor and a control unit. The detector may detect interacted photons generated by illuminating a sample and generate test data. The sensor may be configured to sense an operating condition and transmit this information to the control unit which is configured to search a look-up table to determine the appropriate instrument response correction.
1 . A method comprising:
acquiring test data at a first operating point, wherein said test data comprises an intensity response representative of a reference sample;
based on said first operating point, searching a look-up table to thereby determine an instrument response correction, wherein said look-up table comprises:
a plurality of instrument response corrections, and
wherein each instrument response correction corresponds to an intensity response representative of said reference sample at an operating point; and
applying said instrument response correction to said test data.
2 . The method of claim 1 further comprising constructing said look-up table by:
operating a system to thereby record an intensity response representative of a reference sample at each of a plurality of operating points.
3 . The method of claim 1 wherein said test data comprises Raman test data.
4 . The method of claim 3 wherein said Raman test data comprises a Raman hyperspectral image.
5 . The method of claim 1 wherein said test data comprises test data selected from the group consisting of: short wave infrared test data, near infrared test data, mid wave infrared test data, long wave infrared test data, and combinations thereof.
6 . The method of claim 5 wherein said short wave infrared test data comprises a short wave infrared hyperspectral image.
7 . The method of claim 5 wherein said near infrared test data comprises a near infrared hyperspectral image.
8 . The method of claim 5 wherein said mid wave infrared test data comprises a mid wave hyperspectral image.
9 . The method of claim 5 wherein said long wave infrared test data comprises a long wave hyperspectral image.
10 . The method of claim 1 further comprising, acquiring said test data by:
illuminating a reference sample to thereby generate a plurality of interacted photons;
passing said plurality of interacted photons through a tunable filter to thereby sequentially filter said plurality of interacted photons into a plurality of predetermined wavelength bands;
detecting said plurality of interacted photons to thereby generate test data representative of said reference sample.
11 . The method of claim 1 wherein said operating point comprises an environmental operating point.
12 . The method of claim 11 wherein said environmental operating point is selected from the group consisting of: a temperature, a humidity, an atmospheric pressure, and combinations thereof.
13 . A data storage medium containing program code, which, when executed by a processor causes said processor to perform the following:
acquire test data at a first operating point, wherein said test data comprises an intensity response representative of a reference sample;
based on said first operating point, search a look-up table to thereby determine an instrument response correction, wherein said look-up table comprises
a plurality of instrument response corrections, and
wherein each instrument response correction corresponds to an intensity response representative of said reference sample at an operating point; and
apply said instrument response correction to said test data.
14 . The data storage medium containing program code of claim 13 , which, when executed by a processor further causes said processor to construct said look-up table by:
operating a system to thereby record an intensity response representative of a reference sample at each of a plurality of operating points.
15 . The data storage medium containing program code of claim 13 , which, when executed by a processor further causes said processor to acquire said test data by:
illuminating a reference sample to thereby generate a plurality of interacted photons;
passing said plurality of interacted photons through a tunable filter to thereby sequentially filter said plurality of interacted photons into a plurality of predetermined wavelength bands;
detecting said plurality of interacted photons to thereby generate test data representative of said reference sample.
16 . A system comprising:
an illumination source to illuminate a sample to thereby generate a first plurality of interacted photons;
a collection optics configured to collect said first plurality of interacted photons;
a liquid crystal-based tunable optical filter configured to sequentially filter said first plurality of interacted photons into a plurality of predetermined wavelength bands;
at least one detector configured to detect said first plurality of interacted photons and thereby generate test data representative of said sample;
at least one sensor configured so as to sense at least one operating point;
a control unit configured to:
receive said operating point from said sensor, and
based on said operating point, searching a look-up table to thereby determine an instrument response correction.