IP Library › Granted Patent US 8,101,737
Granted Patent B2
US 8,101,737 · App. 12/938,262 · Granted Jan 24, 2012

Parallel preparation of high fidelity probes in an array format

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Quick Facts
Patent No.
US 8,101,737
App. No.
12/938,262
Granted
Jan 24, 2012
Kind
B2
Abstract

The present invention provides massively parallel oligonucleotide synthesis and purification for applications that utilize large collections of defined high-fidelity oligonucleotides (e.g., from about 10 1 to about 10 5 different sequences, generally between 25-160 bases in length).

Claims (12)

1. A compound represented by the following structural formula:

wherein:

X is an oligonucleotide or a peptide;

R 1 , R 2 , and R 3 , are each independently H, or R 1 and R 2 form a fused aryl ring, or

R 3 is aryl; and

Ar is aryl.

2. The compound of claim 1 , represented by the following structural formula:

wherein:

R 1 and R 2 form a fused aryl ring.

3. The compound of claim 1 , represented by the following structural formula:

4. The compound of claim 1 , represented by the following structural formula:

5. The compound of claim 1 , represented by the following structural formula:

Assignments (4)
NOTICE OF RELEASE Recorded Apr 5, 2016
From: BANK OF AMERICA, N.A.
To: AFFYMETRIX, INC.
Reel/Frame 038361/0891 →
RELEASE OF SECURITY INTEREST Recorded Nov 13, 2015
From: GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT
To: AFFYMETRIX, INC.
Reel/Frame 037109/0132 →
SECURITY INTEREST Recorded Oct 28, 2015
From: AFFYMETRIX, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 036988/0166 →
SECURITY AGREEMENT Recorded Jun 27, 2012
From: AFFYMETRIX, INC.
To: GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT
Reel/Frame 028465/0541 →