The present invention relates to a method for treating recurrent tumor metastases following liver resection that includes administration of an effective amount of an agonist of A 2A adenosine receptors (ARs).
1. A method for treating liver tumor micrometastases following liver resection, comprising:
administering to a patient experiencing liver metastases a therapeutically effective amount of an A 2A adenosine receptor agonist of formula 1 or 2 or a stereoisomer or pharmaceutically acceptable salt thereof:
2. The method of claim 1 , wherein the A 2A adenosine receptor agonist is a compound of the following formula or a pharmaceutically acceptable salt thereof:
3. The method of claim 1 , wherein the A 2A adenosine receptor agonist is a compound of the following formula or a pharmaceutically acceptable salt thereof:
4. The method of claim 1 , wherein the agonist is administered prior to liver resection.
5. The method of claim 1 , wherein the agonist is administered during liver resection.
6. The method of claim 1 , wherein the agonist is administered post liver resection.
7. The method of claim 1 , wherein the agonist is administered prior to and post liver resection.