Tissue ablation systems and methods
View Patent ↗Tissue is treated using a radiofrequency power supply connected to an applicator having a chamber filled with an electrically non-conductive gas surrounded by a thin dielectric wall. A radiofrequency voltage is applied at a level sufficient to ionize the gas into a plasma and to capacitively couple the ionized plasma with the tissue to deliver radiofrequency current to ablate or otherwise treat the tissue.
1. A method of applying energy to tissue comprising:
contacting tissue with a thin-wall energy-delivery construct; and
causing spatiotemporal switching of focal points of energy application about the construct by coupling energy to said focal points with transitory plasma streamers.
2. The method of claim 1 wherein the energy-delivery construct has a first surface interfacing with tissue and a second surface interfacing with the plasma streamers.
3. The method of claim 1 wherein the applied energy includes Joule heating of tissue from current coupled through the construct by the plasma streamers.
4. The method of claim 1 wherein the applied energy includes conductive heating of tissue adjacent the first surface.
5. The method of claim 1 wherein the switching step includes altering the electron-permeability of said construct.
6. The method of claim 2 wherein the switching step includes applying sufficient voltage across a gas to create the plasma streamers.
7. The method of claim 5 wherein the switching step includes providing first and second electrodes positioned respectively at an exterior and interior of the construct and applying voltage between the electrodes to create the plasma streamers.
8. The method of claim 1 wherein the temporal aspect of the switching step occurs within less than milliseconds.
9. The method of claim 1 wherein the spatial aspect of the switching step moves the focal points apart from one.
10. The method of claim 1 wherein the spatial aspect of the switching step moves the focal points to substantially cover the energy-delivery construct in contact with tissue.
11. The method of claim 1 wherein the energy-delivery construct comprises a dielectric.
12. The method of claim 1 wherein contacting step includes deploying the energy-delivery construct interstitially.
13. The method of claim 1 wherein contacting step includes deploying the energy-delivery construct in a body lumen, space or cavity.
14. The method of claim 1 wherein contacting step included expanding an energy-delivery construct from a compacted configuration to an expanded configuration.
15. A method of applying energy to tissue comprising:
contacting tissue with a thin dielectric wall; and
causing spatiotemporal switching of focal points of energy application about the wall by coupling energy to said focal points with transitory plasma streamers;
wherein the focal points apply energy to tissue by Joule heating.
16. A method of applying energy to tissue comprising:
contacting tissue with a thin dielectric wall; and
causing spatiotemporal switching of focal points of energy application about the wall by coupling energy to said focal points with transitory plasma streamers;
wherein the focal points apply energy to tissue by conductive heating.
17. A method of applying electrosurgical energy to tissue comprising:
engaging tissue with first surface of a dielectric barrier; and
coupling RF current to a second surface of the dielectric barrier through a plasma, wherein dielectric material momentarily concentrates electrostatic lines of flux allowing RF current across the dielectric barrier to the tissue.
18. The method of claim 17 , wherein coupling RF current to the second surface is accomplished by plasma filaments.
19. The method of claim 18 , wherein the plasma filaments extend from at least one electrode to the second surface.
20. The method of claim 19 , wherein the plasma filaments are within a gas in an interior chamber surrounded at least in part by the dielectric barrier.
21. The method of claim 17 , further comprising utilizing a controller to limit spatiotemporal chaos of the plasma filaments.
22. The method of claim 17 , further comprising utilizing a controller to spatiotemporally control the plasma filaments.
23. The method of claim 17 , further comprising utilizing a controller to create a spatiotemporally pattern of plasma filaments.
24. The method of claim 23 , wherein controlling the plasma filaments further spatiotemporally controls the electrostatic lines of flux.
25. The method of claim 23 , wherein the controller controls RF voltage.
26. The method of claim 23 , wherein the controller controls a flow of gas in which the plasma filaments occur.