Ingestible circuitry
The present invention provides for safe and reliable electronic circuitry that can be employed in ingestible compositions. The ingestible circuitry of the invention includes a solid support; a conductive element; and an electronic component. Each of the support, conductive element and electronic component are fabricated from an ingestible material. The ingestible circuitry finds use in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.
1. An ingestible device comprising:
a support comprising a planar surface;
a first conductive material having a first surface and a second surface, wherein the first surface of the first conductive material is positioned on the planar surface of the support;
an electronic component comprising a digestible second conductive material positioned on the second surface of the first conductive material, wherein the first conductive material is positioned between the second conductive material and the support, wherein the first conductive material is configured to receive an integrated circuit upon the second surface, adjacent to the second conductive material, and provide an electrical interconnect between the second conductive material and the integrated circuit; and
a cover comprising an electrically insulative material deposited over the electronic component, wherein the electrically insulative material comprises a digestible material.
2. The ingestible device according to claim 1 , wherein the digestible material comprises a foodstuff.
3. The ingestible device according to claim 1 , wherein the digestible material is a pharmaceutical excipient.
4. The ingestible device according to claim 1 , wherein the electronic component is selected from the group consisting of:
logic elements, memory elements, power devices, effectors, signal transmission elements and passive elements and combinations thereof.
5. The ingestible device according to claim 4 , wherein the electronic component is an electrode, and wherein the first conductive material comprises a metallic foil.
6. The ingestible device according to claim 1 , wherein the electronic component comprises an electrode comprising multiple discrete deposits of conductive material patterned on the second surface of the first conductive material, and wherein the second conductive material is configured to provide an electrical interconnect between the multiple discrete deposits of first conductive material present on the surface of the first conductive material and the integrated circuit.
7. The ingestible device according to claim 6 , wherein the first conductive material comprises a material selected from the group consisting of gold, silver, graphite and combinations thereof.
8. The ingestible device according to claim 6 , wherein the first conductive material comprises a heterogeneous material.
9. The ingestible device according to claim 6 , wherein the cover defines at least one aperture extending through the cover, wherein the at least one aperture is positioned to provide a fluid path to one or more of the multiple deposits of first conductive material.
10. A method of assembling an ingestible device comprising:
positioning a first conductive material on a planar surface of a support;
positioning an electronic component comprising a digestible second conductive material on a surface of the first conductive material such that the first conductive material is positioned between the support and the electronic component;
positioning an integrated circuit on the surface of the first conductive material, adjacent to the electric component, such that the first conductive material provides an electrical interconnect between the second conductive material and the integrated circuit; and
depositing an electrically insulative digestible material on the electronic component.