Abuse potential reduction in abusable substance dosage form
View Patent ↗The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.
1. A device comprising:
(a) an independent disposable container having an opening therein to receive a skin-worn patch device containing a residual amount of an abusable substance therein;
(b) a layer containing an amount of an anti-abuse substance comprising an adsorption material which is activated carbon that prevents solvent extraction of said abusable substance, said layer being disposed in said container in a manner such that a skin-worn patch device properly inserted into said container will cause said abusable substance to contact said layer containing said anti-abuse substance; and
(c) a closure means for closing said container containing a used skin-worn patch device.
2. The device according to claim 1 , wherein said anti-abuse substance further comprises an agent selected from the group consisting of co-soluble antagonists, irritants and combinations thereof.
3. The device according to claim 1 , wherein said solvent extraction employs a solvent selected from the group consisting of water, ethanol or combinations thereof.
4. The device according to claim 1 , wherein said anti-abuse substance includes an amount of an irritant.
5. The device according to claim 1 , wherein said anti-abuse substance includes an amount of an antagonist.
6. The device according to claim 1 , wherein said container is in the form of a flexible pouch.
7. The device according to claim 1 , wherein said closure device includes an adhesive seal.
8. The device according to claim 1 , wherein said abusable substance is an opioid.
9. The device according to claim 8 , wherein said abusable substance is fentanyl.
10. The device according to claim 1 , wherein said closure means comprises a zip lock seal.
11. The device according to claim 1 , wherein said layer containing an amount of an anti-abuse substance is attached to one side of said container.
12. The device according to claim 1 , wherein said closure means comprises an adhesive strip on each side of said opening of said container.