IP Library › Granted Patent US 8,426,411
Granted Patent B2
US 8,426,411 · App. 12/958,115 · Granted Apr 23, 2013

Tricyclic compounds

Inventors: Neil Wishart (Jefferson, MA); Kristine E. Frank (Worcester, MA); Michael Friedman (Brookline, MA); Dawn M. George (Charlton, MA); Kent D. Stewart (Gurnee, IL); Grier A. Wallace (Sterling, MA)
Assignee: Abbott Laboratories
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Quick Facts
Patent No.
US 8,426,411
App. No.
12/958,115
Granted
Apr 23, 2013
Kind
B2
Abstract

The invention provides compounds of Formula (I) and Formula (II) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

Claims (24)

1. A compound selected from

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

2. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

3. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

4. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

5. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

6. A compound selected from

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

7. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

8. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

9. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

10. A compound selected from

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

11. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

12. A compound represented by the following structure:

or pharmaceutically acceptable salts, stereoisomers and isomers thereof.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 24, 2013
From: ABBOTT LABORATORIES
To: ABBVIE INC.
Reel/Frame 029688/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 25, 2011
From: WISHART, NEIL; ARGIRIADI, MARIA A; CALDERWOOD, DAVID J; ERICSSON, ANNA M; FIAMENGO, BRYAN A; FRANK, KRISTINE E; FRIEDMAN, MICHAEL; GEORGE, DAWN M; GOEDKEN, ERIC R; JOSEPHSOHN, NATHAN S; LI, BIQIN C; MORYTKO, MICHAEL J; STEWART, KENT D; VOSS, JEFFREY W; WALLACE, GRIER A; WANG, LU; WOLLER, KEVIN R
To: ABBOTT LABORATORIES
Reel/Frame 026337/0022 →
Continuity (3)
Provisional Application 61265563 · Dec 1, 2009
Provisional Application 61364116 · Jul 14, 2010
Related Publication 20110311474A1 · Dec 22, 2011