Use of (R)-Penciclovir Triphosphate for the Manufacture of a Medicament for the Treatment of Viral Diseases
A method of treatment of: i) HIV-1 infections in mammals, including humans; or ii) HBV infections in mammals, including humans; which method comprises the administration to the human in need of such treatment, an effective amount of the (R)-enantiomer of the triphosphate of a compound of formula (A) or a pharmaceutically acceptable salt thereof; and compounds for use in the method.
1 . A method of treatment of:
i) HIV-1 infections in mammals, including humans; or
ii) HBV infections in mammals, including humans;
which method comprises the administration to the human in need of such treatment, an effective amount of the (R)-enantiomer of the triphosphate of a compound of formula (A):
((R)-PCV-TP), or a pharmaceutically acceptable salt thereof.
2 . (canceled)
3 . (canceled)
4 . A method, composition, or use according to claim 1 wherein the (R)-PCV-TP is in the form of a bioprecursor which is a derivative of (R)-PCV-MP which liberates intracellularly (R)-PCV-MP which is in turn converted to (R)-PCV-TP.
5 . (canceled)
6 . (canceled)
7 . (canceled)