IP Library Granted Patent US 8,632,825
Granted Patent B2
US 8,632,825 · App. 12/996,124 · Granted Jan 21, 2014

Anti-tumoural effects of cannabinoid combinations

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Quick Facts
Patent No.
US 8,632,825
App. No.
12/996,124
Granted
Jan 21, 2014
Kind
B2
Abstract

The invention relates to the use of a combination of cannabinoids, particularly tetrahydrocannabinol (THC) and cannabidiol (CBD), in the manufacture of a medicament for use in the treatment of cancer. In particular the cancer to be treated is a brain tumor, more particularly a glioma, more particularly still a glioblastoma multiforme (GBM).

Claims (3)

1. A method for treating glioblastoma multiforme in a human in need thereof consisting essentially of administering to said human therapeutically effective amounts of cannabidiol (CBD) and tetrahydrocannabinol (THC) in combination as pure cannabinoids wherein the cannabinoids are in a ratio of from 1:1 to 1:20 (THC:CBD).

2. The method of claim 1 , wherein the treatment of the glioblastoma multiforme in a human in need thereof is to reduce cell viability, reduce cell growth or reduce tumour volume.

3. The method of claim 1 , wherein the THC and CBD are administered separately, sequentially or simultaneously to said human.

Assignments (4)
CHANGE OF NAME Recorded May 13, 2025
From: GW PHARMA LIMITED
To: JAZZ PHARMACEUTICALS OPERATIONS UK LIMITED
Reel/Frame 071103/0054 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 12, 2023
From: OTSUKA PHARMACEUTICAL CO., LTD.
To: GW PHARMA LTD.
Reel/Frame 063631/0588 →
SECURITY AGREEMENT Recorded Jul 22, 2021
From: GW PHARMA LIMITED; GW RESEARCH LIMITED
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 056958/0493 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2011
From: DIEZ, GUILLERMO VELASCO; PASTOR, MANUEL GUZMAN; LORENTE, MAR; TORRES, SOFIA; RODRIGUEZ, FATIMA
To: GW PHARMA LIMITED; OTSUKA PHARMACEUTICAL CO., LTD.
Reel/Frame 025892/0360 →