Analyzing device
View Patent ↗An analyzing device includes: an operation cavity that is adjacent to a first reserving cavity retaining a sample liquid; a connecting section provided on a side wall of the first reserving cavity to suck the sample liquid by a capillary force and transfer the sample liquid to the operation cavity; and second reserving cavities that are disposed outside the operation cavity in the circumferential direction of the rotational driving and communicate with the outermost position of the operation cavity through a connecting passage. The connecting section is circumferentially extended farther than the liquid level of the sample liquid retained in the first reserving cavity.
1. An analyzing device having a microchannel structure for transferring a sample liquid to a measurement spot by a centrifugal force generated by rotating the analyzing device about a rotation axis, the analyzing device being configured to allow measurement of a reaction liquid at the measurement spot,
the analyzing device comprising:
a first reserving cavity that retains a sample liquid transferred by the centrifugal force, the first reserving cavity being formed with a clearance in which a capillary force is not applied to move the sample liquid;
an operation cavity that is adjacent to the first reserving cavity in a circumferential direction relative to the rotation axis, a maximum cross section dimension in a thickness direction of the operation cavity being smaller than a maximum cross section dimension in a thickness direction of the first reserving cavity, the maximum cross section dimension in a thickness direction of the operation cavity being configured to create a capillary force in the operation cavity when the analyzing device is not rotated, the thickness direction of the operation cavity and the thickness direction of the first reserving cavity being parallel to the rotation axis;
a reagent retained in the operation cavity;
a connecting section in direct fluid communication with the operation cavity and the first reserving cavity, the connection section being disposed on an inside wall surface of the first reserving cavity, the connecting section having a cross section dimension in a thickness direction that is configured to be sufficiently small to cause a capillary force in the connecting section to transfer the sample liquid from the first reserving cavity to the operation cavity when the analyzing device is not rotated, the thickness direction of the connecting section being parallel to the rotation axis, the connecting section including a first end formed toward an outer circumference of the first reserving cavity, and a second end connecting to the operation cavity, the first end being located further from the rotation axis than the second end;
a vent cavity that communicates with an outside atmosphere located next to the operation cavity at an inner periphery side of the operation cavity, the vent cavity being in fluid communication with an inner periphery of the operation cavity;
a communicating section that communicates the vent cavity with the first reserving cavity, the communicating section being located closer to the rotation axis than the connecting section; and
a second reserving cavity that is disposed further away from the rotation axis than the operation cavity, the second reserving cavity being formed with a clearance in which a capillary force is not applied to move the sample liquid, the second reserving cavity communicating with an outermost position of the operation cavity via a connecting passage, and retaining the sample liquid transferred from the operation cavity by the centrifugal force,
wherein the first end of the connecting section extends to the outer circumference of the first reserving cavity, and the second end of the connecting section is connected to the operation cavity at a location closer to the rotation axis than a liquid level of the sample liquid retained in the first reserving cavity when the centrifugal force is applied, and
wherein the entire connecting section is disposed within the first reserving cavity.
2. The analyzing device according to claim 1 , wherein a through hole is provided at the first reserving cavity, the operation cavity being communicated with atmosphere via the through hole, the communicating section and the cavity.
3. The analyzing device according to claim 1 , wherein the connecting passage has cross sectional dimensions in a thickness direction and the cross sectional dimensions are smaller than cross sectional dimensions in a thickness direction of the operation cavity.
4. The analyzing device according to claim 1 , wherein the operation cavity contains reagents and an agitating rib, the agitating rib extending in a radial direction between the reagents.
5. The analyzing device according to claim 1 , wherein communication between the inner periphery of the operation cavity and the vent cavity allows a space not filled with the sample liquid to be generated at the inner periphery of the operation cavity.
6. The analyzing device according to claim 1 , wherein the sample liquid is blood.