Compositions and methods for enhancing and treating female sexual response
View Patent ↗The present invention relates to compositions, articles of manufacture, methods of preparation thereof, methods of use thereof, etc., for enhancement of sexual pleasure, conditions, disorders, and diseases related to reproductive physiology and systems, especially of mammalian females. For instance, the present invention relates to all aspects of modulating the female sexual response, including female sexual dysfunction, such as female sexual arousal disorders (FSAD), orgasmic disorders, and sexual pain disorders, and enhancing female sexual pleasure and satisfaction of the female sexual experience. Accordingly, the present invention relates to compositions comprising botanical extracts, active agents, etc., which are useful to treat or affect any of the aforementioned conditions. For example, the present invention relates to a composition, preferably for topical or local use, which comprises one or more of the following ingredients, including, but not limited to, borage seed oil, Angelica pubescens root and other angelica species, Coleus forskohlii extract, vinpocetine, ferulic acid, magnesium, ascorbyl palmitate, capric/caprylic triglyceride, silica, and equivalents thereof.
1. A topical composition for application to the external female genitalia or vagina, consisting essentially of:
borage seed oil;
Angelica pubescens ; and
Coleus forskolhii;
wherein the amount of the borage seed oil, Angelica pubescens , and Coleus forskolhii in the composition are effective for improving female sexual pleasure, female sexual arousal, treating female sexual arousal disorder, female orgasmic disorder, or female sexual pain disorder.
2. The topical composition of claim 1 , further comprising a pharmaceutically acceptable topical excipient.
3. The topical composition of claim 1 , further comprising Vitamin E, Vitamin E acetate or salts thereof, or a combination thereof.
4. The topical composition of claim 1 , further comprising one or more antioxidants.
5. The topical composition of claim 1 , wherein the one or more antioxidants comprise ascorbic acid.
6. The topical composition of claim 1 , wherein the borage seed oil comprises 10-95% w/w of the composition.
7. The topical composition of claim 1 , wherein the Coleus forskohlii comprises 0.001-8% w/w of the composition.
8. The topical composition of claim 1 , further comprising a flavoring agent.
9. The topical composition of claim 8 , wherein the flavoring agent is selected from the group consisting of saccharin, monsodium gaunosine mono phosphate, blackberry, and lavender.
10. The topical composition of claim 8 , wherein the flavoring agent is a sweetening agent.
11. A topical composition for application to the external female genitalia or vagina, consisting essentially of:
borage seed oil;
Angelica pubescens;
Coleus forskolhii ; and
evening primrose oil;
wherein the amount of the borage seed oil, Angelica pubescens, Coleus forskolhii , and evening primrose oil in the composition are effective for improving female sexual pleasure, female sexual arousal, treating female sexual arousal disorder, female orgasmic disorder, or female sexual pain disorder.
12. The topical composition of claim 11 , further comprising a pharmaceutically acceptable topical excipient.
13. The topical composition of claim 11 , further comprising Vitamin E, Vitamin E acetate or salts thereof, or a combination thereof.
14. The topical composition of claim 11 , further comprising one or more antioxidants.
15. The topical composition of claim 11 , wherein the one or more antioxidants comprise ascorbic acid.
16. The topical composition of claim 11 , wherein the borage seed oil comprises 10-95% w/w of the composition.
17. The topical composition of claim 11 , wherein the Coleus forskohlii comprises 0.001-8% w/w of the composition.
18. The topical composition of claim 11 , further comprising a flavoring agent.
19. The topical composition of claim 18 , wherein the flavoring agent is selected from the group consisting of saccharin, monsodium gaunosine mono phosphate, blackberry, and lavender.
20. The topical composition of claim 18 , wherein the flavoring agent is a sweetening agent.