IP Library Granted Patent US 8,361,053
Granted Patent B2
US 8,361,053 · App. 13/013,379 · Granted Jan 29, 2013

Multi-cartridge fluid delivery device

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Quick Facts
Patent No.
US 8,361,053
App. No.
13/013,379
Granted
Jan 29, 2013
Kind
B2
Abstract

A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.

Claims (44)

1. A method of administering first and second medicaments from a fluid delivery device, the method comprising:

forcing hydraulic fluid from a hydraulic fluid reservoir into a first pump chamber, the hydraulic fluid in the first pump chamber exerting a force on a first piston to expel at least a portion of the first medicament through an aperture of a first fluid reservoir and deliver a first basal delivery of the first medicament;

forcing hydraulic fluid from the hydraulic fluid reservoir into a second pump chamber, the hydraulic fluid in the second pump chamber exerting a force on a second piston to expel at least a portion of the second medicament through an aperture of a second fluid reservoir and deliver a second basal delivery of the second medicament.

2. The method of claim 1 , wherein forcing hydraulic fluid from the hydraulic fluid reservoir includes applying a spring force to a piston within the hydraulic fluid reservoir.

3. The method of claim 1 , wherein forcing the hydraulic fluid from the hydraulic fluid reservoir includes forcing hydraulic fluid from the hydraulic fluid reservoir through a flow restrictor and into the first and second pump chambers.

4. A method of administering first and second medicaments from a fluid delivery device, the method comprising:

delivering a first basal delivery of the first medicament, and

delivering a second basal delivery of the second medicament,

wherein the fluid delivery device comprises:

a housing;

a first reservoir within the housing and configured to contain the first medicament;

a second reservoir within the housing and configured to contain the second medicament;

a first basal drive mechanism within the housing and having a first hydraulic fluid reservoir;

a first pump chamber in fluid communication with the first hydraulic fluid reservoir of the first basal drive mechanism via a first flow restrictor, the first pump chamber configured to engage the first reservoir to provide a basal delivery of the first medicament during use;

a second basal drive mechanism within the housing and having a second hydraulic fluid reservoir;

a second pump chamber in fluid communication with the second hydraulic fluid reservoir of the second basal drive mechanism via a second flow restrictor, the second pump chamber configured to engage the second reservoir to provide a basal delivery of the second medicament during use; and

a needle having a first end configured for fluid communication with the first reservoir and a second end configured to extend exteriorly from the housing.

5. The method of claim 4 , wherein the fluid delivery device further comprises a bolus drive mechanism coupled to the first pump chamber and configured to provide a bolus delivery of the first medicament.

6. The method of claim 5 , wherein the bolus drive mechanism is coupled to the second pump chamber and is configured to provide a bolus delivery of the second medicament.

7. The method of claim 5 , wherein the bolus drive mechanism is a first bolus drive mechanism and wherein the fluid delivery device further comprises a second bolus drive mechanism coupled to the second pump chamber and configured to provide a bolus delivery of the second medicament.

8. The method of claim 5 , wherein the bolus drive mechanism includes a ratchet and a bolus piston coupled to the ratchet.

9. The method of claim 8 , wherein the bolus of the first medicament is larger than the bolus of the second medicament.

10. The method of claim 4 , wherein the first and second basal drive mechanisms each include a coil spring coupled to a drive piston.

11. The method of claim 4 , wherein the fluid delivery device further comprises a first delivery piston coupled to the first pump chamber and positioned within the first fluid reservoir to exert a force on the first medicament within the first fluid reservoir and a second delivery piston coupled to the second pump chamber and positioned within the second fluid reservoir to exert a force on the second medicament within the second fluid reservoir.

12. The method of claim 4 , wherein the fluid delivery device is an ambulatory infusion pump.

13. The method of claim 4 , wherein the needle includes a third end configured for fluid communication with the second reservoir.

14. The method of claim 4 , wherein the needle configured for fluid communication with the first reservoir is a first needle, the fluid delivery device further comprising a second needle configured for fluid communication with the second reservoir.

15. A method of administering first and second medicaments from a fluid delivery device, the method comprising:

delivering a first basal delivery of the first medicament, and

delivering a second basal delivery of the second medicament,

wherein the fluid delivery device comprises:

a housing;

a first reservoir within the housing and configured to contain the first medicament;

a second reservoir within the housing and configured to contain the second medicament;

a basal drive mechanism within the housing and having a hydraulic fluid reservoir;

a first pump chamber in fluid communication with the hydraulic fluid reservoir of the basal drive mechanism via a first flow restrictor, the first pump chamber configured to engage the first reservoir to provide basal delivery of the first medicament during use; and

a second pump chamber in fluid communication with the hydraulic fluid reservoir of the basal drive mechanism via a second flow restrictor, the second pump chamber configured to engage the second reservoir to provide basal delivery of the second medicaments during use.

16. The method of claim 15 , wherein the fluid delivery device further comprises a bolus drive mechanism coupled to the first and second pump chambers to provide bolus deliveries of the first and second medicaments.

17. The method of claim 16 , wherein the bolus drive mechanism includes a ratchet and piston.

18. The method of claim 16 , wherein the bolus of the first medicament is larger than the bolus of the second medicament.

19. The method of claim 15 , wherein the fluid delivery device further comprises a first bolus drive mechanism coupled to the first pump chamber to provide a bolus delivery of the first medicament and a second bolus drive mechanism coupled to the second pump chamber to provide a bolus delivery of the second medicament.

20. The method of claim 15 , wherein the fluid delivery device further comprises a needle having a first end configured for fluid communication with the first reservoir, a second end configured for fluid communication with the second reservoir and a third end configured to engage a user.

21. The method of claim 15 , wherein the fluid delivery device further comprises a first needle configured for fluid communication with the first reservoir and a user and a second needle configured for fluid communication with the second reservoir and the user.

22. The method of claim 15 , wherein the fluid delivery device is an ambulatory infusion pump.

Assignments (11)
SALE ORDER / RELEASE OF SECURITY INTEREST Recorded Aug 18, 2025
From: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: ZEALAND PHARMA A/S
Reel/Frame 072509/0386 →
PATENT SECURITY AGREEMENT Recorded Aug 12, 2025
From: MANNKIND CORPORATION
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 072444/0525 →
RELEASE OF SECURITY INTEREST Recorded May 17, 2023
From: ZOOLANDER SA LLC
To: ZEALAND PHARMA A/S
Reel/Frame 063672/0342 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 2, 2022
From: ZEALAND PHARMA A/S
To: MANNKIND CORPORATION
Reel/Frame 060984/0295 →
RELEASE OF SECURITY INTEREST Recorded Aug 24, 2022
From: ZOOLANDER SA LLC
To: ZEALAND PHARMA A/S
Reel/Frame 060887/0685 →
PATENT SECURITY AGREEMENT Recorded Dec 27, 2021
From: ZEALAND PHARMA A/S
To: ZOOLANDER SA LLC
Reel/Frame 058593/0261 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 6, 2020
From: VALERITAS, INC.
To: ZEALAND PHARMA A/S
Reel/Frame 052859/0390 →
SHORT-FORM PATENT SECURITY AGREEMENT Recorded May 28, 2013
From: VALERITAS, INC.
To: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
Reel/Frame 030497/0800 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2011
From: GONNELLI, ROBERT; LEVESQUE, STEVEN F.; NARDI, RONALD V.
To: BIOVALVE TECHNOLOGIES, INC
Reel/Frame 025694/0193 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2011
From: BIOVALVE TECHNOLOGIES, INC.
To: VALERITAS, LLC
Reel/Frame 025694/0233 →
CHANGE OF NAME Recorded Jan 25, 2011
From: VALERITAS LLC
To: VALERITAS, INC.
Reel/Frame 025694/0898 →